Evidence map›Paper›PMID 35337016›Full record

ReviewViruses2022

Gene-Edited Cell Models to Study Chronic Wasting Disease.

Simrika Thapa, Cristobal Marrero Winkens, Waqas Tahir, Maria I Arifin, Sabine Gilch, Hermann M Schatzl

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. A Neuronal Cell Line Model for Studying Camel Prions.Pathogens (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Simrika ThapaCalgary Prion Research Unit, University of Calgary, Calgary, AB T2N 4Z6, Canada.
Cristobal Marrero WinkensCalgary Prion Research Unit, University of Calgary, Calgary, AB T2N 4Z6, Canada.
Waqas TahirCalgary Prion Research Unit, University of Calgary, Calgary, AB T2N 4Z6, Canada.
Maria I ArifinCalgary Prion Research Unit, University of Calgary, Calgary, AB T2N 4Z6, Canada.
Sabine GilchCalgary Prion Research Unit, University of Calgary, Calgary, AB T2N 4Z6, Canada.ORCID 0000-0001-5923-3464
Hermann M SchatzlCalgary Prion Research Unit, University of Calgary, Calgary, AB T2N 4Z6, Canada.ORCID 0000-0003-4972-8740
University of Calgary · CACanadian Food Inspection Agency · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prion diseases are fatal infectious neurodegenerative disorders affecting both humans and animals. They are caused by the misfolded isoform of the cellular prion protein (PrP

Indexed as

DeerPrion DiseasesPrionsWasting Disease, ChronicAnimalsGene EditingMicePrion ProteinsPrion ProteinsPrionscell culture modelschronic wasting diseaseCRISPR-Cas9CWDgene-edited cellsgene-editingknock-inknock-outprionprion disease

Identifiers

PMID35337016
PMCPMC8950194
OpenAlexW4220832512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.