Evidence map›Paper›PMID 35336980›Full record

ReviewViruses2022

COVID-19 at a Glance: An Up-to-Date Overview on Variants, Drug Design and Therapies.

Domenico Iacopetta, Jessica Ceramella, Alessia Catalano, Carmela Saturnino, Michele Pellegrino, Annaluisa Mariconda, Pasquale Longo, Maria Stefania Sinicropi, Stefano Aquaro

Abstract readReview
In one paragraph

Review in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. COVID-19-Where Are We Now.Current medicinal chemistry · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Foods (Basel, Switzerland) · 2024
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Targeting Breast Cancer: An Overlook on Current Strategies.International journal of molecular sciences · 2023
    Review
  18. Biological Activities of Ruthenium NHC Complexes: An Update.Antibiotics (Basel, Switzerland) · 2023
    Review
  19. Article
  20. Diarylureas: New Promising Small Molecules againstAntibiotics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Domenico IacopettaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.ORCID 0000-0001-5179-7118
Jessica CeramellaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.ORCID 0000-0002-1386-3601
Alessia CatalanoDepartment of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", 70126 Bari, Italy.ORCID 0000-0002-7420-4706
Carmela SaturninoDepartment of Science, University of Basilicata, 85100 Potenza, Italy.ORCID 0000-0002-7419-8780
Michele PellegrinoDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.
Annaluisa MaricondaDepartment of Science, University of Basilicata, 85100 Potenza, Italy.
Pasquale LongoDepartment of Chemistry and Biology, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano, Italy.ORCID 0000-0002-7685-1093
Maria Stefania SinicropiDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.ORCID 0000-0003-2435-8931
Stefano AquaroDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.ORCID 0000-0002-8417-2103

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a member of the Coronavirus family which caused the worldwide pandemic of human respiratory illness coronavirus disease 2019 (COVID-19). Presumably emerging at the end of 2019, it poses a severe threat to public health and safety, with a high incidence of transmission, predominately through aerosols and/or direct contact with infected surfaces. In 2020, the search for vaccines began, leading to the obtaining of, to date, about twenty COVID-19 vaccines approved for use in at least one country. However, COVID-19 continues to spread and new genetic mutations and variants have been discovered, requiring pharmacological treatments. The most common therapies for COVID-19 are represented by antiviral and antimalarial agents, antibiotics, immunomodulators, angiotensin II receptor blockers, bradykinin B2 receptor antagonists and corticosteroids. In addition, nutraceuticals, vitamins D and C, omega-3 fatty acids and probiotics are under study. Finally, drug repositioning, which concerns the investigation of existing drugs for new therapeutic target indications, has been widely proposed in the literature for COVID-19 therapies. Considering the importance of this ongoing global public health emergency, this review aims to offer a synthetic up-to-date overview regarding diagnoses, variants and vaccines for COVID-19, with particular attention paid to the adopted treatments.

Indexed as

COVID-19 Drug TreatmentAntiviral AgentsCOVID-19 VaccinesDrug DesignHumansSARS-CoV-2Antiviral AgentsCOVID-19 VaccinesCOVID-19drugsnutraceuticalspandemicrepositioningrepurposingSARS-CoV-2therapiesvaccines

Identifiers

PMID35336980
PMCPMC8950852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.