Evidence map›Paper›PMID 35336897›Full record

ArticleViruses2022

Immune Response of an Oral

Beatriz Garcia Mendes, Yi Duan, Bernd Schnabl

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06750588 (Phase 1, Open Label Study to Evaluate Safety and Tolerability of NTR-101 in Patients With Acute Alcohol-Associated Hepatitis), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06750588 phase1not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Phase 1, Open Label Study to Evaluate Safety and Tolerability of NTR-101 in Patients With Acute Alcohol-Associated Hepatitis

TypeinterventionalSponsorNterica Bio incRan2025 to 2026Enrolled12ConditionsAlcohol-Associated HepatitisArmsbacteriophage preparation, Bacteriophage preparation
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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  5. Article
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  10. Isolation and identification of specificFrontiers in microbiology · 2024
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Beatriz Garcia MendesDepartment of Medicine, University of California San Diego, La Jolla, San Diego, CA 92093, USA.
Yi DuanDepartment of Medicine, University of California San Diego, La Jolla, San Diego, CA 92093, USA.
Bernd SchnablDepartment of Medicine, University of California San Diego, La Jolla, San Diego, CA 92093, USA.
University of California, San Diego · US

Funding

The Southernearch Center for ALPD and CirrhosisP50AA011999 · NIAAA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ANNA S. GUKOVSKAYA · 1999 to 2026
$45.8M
San Diego Digestive Diseases Research CenterP30DK120515 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LARS ECKMANN · 2019 to 2026
$10.8M
The Role of the Intestinal Mycobiome in Alcoholic Liver DiseaseR01AA024726 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Bernd G. Schnabl · 2018 to 2026
$3.9M
Microbiome and Intestinal Innate Immune Response in Alcoholic Liver DiseaseR37AA020703 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Bernd G. Schnabl · 2021 to 2026
$2.5M
Microbiome as therapeutic target in alcoholic hepatitisU01AA026939 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FOUTS, DERRICK E, SCHNABL, BERND G. · 2018 to 2022
$1.7M
The role of pathobionts in alcoholic liver diseaseI01BX004594 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI Bernd G. Schnabl · 2019 to 2026
–
Molecular Mechanisms of Stellate Cell Activation in Liver FibrosisI01BX001991 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI HIDEKAZU TSUKAMOTO · 2014 to 2026
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BLRD VA I01 BX004594NIAAA NIH HHS P50 AA011999NIAAA NIH HHS R01 AA24726NIAAA NIH HHS R37 AA020703NIAAA NIH HHS U01 AA026939NIDDK NIH HHS P30 DK120515
6 · The paper itself

Abstract

Cytolysin-positive

Indexed as

BacteriophagesLiver DiseasesAnimalsEnterococcus faecalisEthanolImmunityMicePerforinEthanolPerforinalcoholic hepatitisEnterococcus faecalishost rangeimmune responsephage therapyphage translocation

Identifiers

PMID35336897
PMCPMC8955932
OpenAlexW4214617672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.