Evidence map›Paper›PMID 35336895›Full record

ArticleViruses2022

The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals.

Fenghua Wang, Cheng Chen, Zefang Wang, Xu Han, Peidian Shi, Kaixuan Zhou, Xiaomei Liu, Yunjie Xiao, Yan Cai, Jinhai Huang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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  5. Future science OA · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Fenghua WangSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Cheng ChenSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Zefang WangSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Xu HanSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Peidian ShiSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Kaixuan ZhouTianjin International Joint Academy of Biotechnology and Medicine, Tianjin 300457, China.
Xiaomei LiuTianjin International Joint Academy of Biotechnology and Medicine, Tianjin 300457, China.
Yunjie XiaoSchool of Life Sciences, Tianjin University, Tianjin 300072, China.ORCID 0000-0002-2278-6900
Yan CaiTianjin International Joint Academy of Biotechnology and Medicine, Tianjin 300457, China.
Jinhai HuangSchool of Life Sciences, Tianjin University, Tianjin 300072, China.ORCID 0000-0002-1073-533X
Lei ZhangSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Haitao YangSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Tianjin University · CNTianjin International Joint Academy of Biomedicine · CNTianjin University of Science and Technology · CN

Funding

Lingang Laboratory LG202101-01-07National Key R&D Program of China 2020YFA0707502National Natural Science Foundation of China 92169109Science and Technology Commission of Shanghai Municipality 20XD1422900Science and Technology Commission of Shanghai Municipality YDZX20213100001556
6 · The paper itself

Abstract

The existing zoonotic coronaviruses (CoVs) and viral genetic variants are important microbiological pathogens that cause severe disease in humans and animals. Currently, no effective broad-spectrum antiviral drugs against existing and emerging CoVs are available. The CoV main protease (M

Indexed as

Antiviral AgentsCoronavirusAnimalsDeltacoronavirusPeptide HydrolasesSwineAntiviral AgentsPeptide Hydrolasesbroad-spectrum antiviralscoronavirusesmain proteaseporcine deltacoronavirus

Identifiers

PMID35336895
PMCPMC8949103
OpenAlexW4214627146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.