Evidence map›Paper›PMID 35336804›Full record

ArticleBiology2022

The VIP/VPAC1R Pathway Regulates Energy and Glucose Homeostasis by Modulating GLP-1, Glucagon, Leptin and PYY Levels in Mice.

Daniel Sanford, Leon Luong, John P Vu, Suwan Oh, Arielle Gabalski, Michael Lewis, Joseph R Pisegna, Patrizia Germano

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Daniel SanfordResearch Service, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA.
Leon LuongResearch Service, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA.
John P VuResearch Service, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA.
Suwan OhResearch Service, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA.ORCID 0000-0002-6779-1690
Arielle GabalskiResearch Service, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA.
Michael LewisDepartment of Pathology, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA.
Joseph R PisegnaDigestive Diseases Research Center (CURE), Department of Medicine, University of California, Los Angeles, CA 90073, USA.
Patrizia GermanoResearch Service, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA.
University of California, Los Angeles · USVA Greater Los Angeles Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vasoactive Intestinal Peptide binds with high affinity to VPAC1R and VPAC2R, thus regulating key physiologic functions. Previously, we documented in VIP

Indexed as

calorimetryGLP-1glucagonglucoseleptinPYYVIPVPAC1R

Identifiers

PMID35336804
PMCPMC8945135
OpenAlexW4220652442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.