Evidence map›Paper›PMID 35336793›Full record

ReviewBiology2022

Draining the Pleural Space: Lymphatic Vessels Facing the Most Challenging Task.

Eleonora Solari, Cristiana Marcozzi, Chiara Ottaviani, Daniela Negrini, Andrea Moriondo

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06964308 (Thoracoscopic Pleural Biopsy, Sohag University Hospital), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06964308 narecruitingnot on this mapstarted 2024, after this paper: background citation

Thoracoscopic Pleural Biopsy, Sohag University Hospital

TypeinterventionalSponsorSohag UniversityRan2024 to 2025Enrolled36ConditionsPleural DiseasesArmsthoracoscopic pleural biopsy.
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Lymphatic System Development and Function.Current cardiology reports · 2024
    Review
  7. Article
  8. Role of Sensory Nerves in Pulmonary Fibrosis.International journal of molecular sciences · 2024
    Review
  9. Article
  10. Review
  11. Fluorescent Tracers forFrontiers in pharmacology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Eleonora SolariDepartment of Medicine and Surgery, School of Medicine, University of Insubria, 21100 Varese, Italy.ORCID 0000-0001-5962-8976
Cristiana MarcozziDepartment of Medicine and Surgery, School of Medicine, University of Insubria, 21100 Varese, Italy.ORCID 0000-0003-2242-2880
Chiara OttavianiDepartment of Medicine and Surgery, School of Medicine, University of Insubria, 21100 Varese, Italy.
Daniela NegriniDepartment of Medicine and Surgery, School of Medicine, University of Insubria, 21100 Varese, Italy.
Andrea MoriondoDepartment of Medicine and Surgery, School of Medicine, University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-9423-5446
University of Insubria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphatic vessels exploit the mechanical stresses of their surroundings together with intrinsic rhythmic contractions to drain lymph from interstitial spaces and serosal cavities to eventually empty into the blood venous stream. This task is more difficult when the liquid to be drained has a very subatmospheric pressure, as it occurs in the pleural cavity. This peculiar space must maintain a very low fluid volume at negative hydraulic pressure in order to guarantee a proper mechanical coupling between the chest wall and lungs. To better understand the potential for liquid drainage, the key parameter to be considered is the difference in hydraulic pressure between the pleural space and the lymphatic lumen. In this review we collected old and new findings from in vivo direct measurements of hydraulic pressures in anaesthetized animals with the aim to better frame the complex physiology of diaphragmatic and intercostal lymphatics which drain liquid from the pleural cavity.

Indexed as

breathingchest walldiaphragmlunglymphatic vesselpleural cavity

Identifiers

PMID35336793
PMCPMC8945018
OpenAlexW4220786877

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.