Evidence map›Paper›PMID 35336183›Full record

ArticleMicroorganisms2022

Genome-Wide Association Study Reveals Host Factors Affecting Conjugation in

Laetitia Van Wonterghem, Matteo De Chiara, Gianni Liti, Jonas Warringer, Anne Farewell, Natalie Verstraeten, Jan Michiels

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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  5. Transfer ofFrontiers in microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Laetitia Van WonterghemCentre of Microbial and Plant Genetics, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0002-6252-7225
Matteo De ChiaraIRCAN, CNRS, INSERM, Université Côte d'Azur, 06107 Nice, France.
Gianni LitiIRCAN, CNRS, INSERM, Université Côte d'Azur, 06107 Nice, France.
Jonas WarringerDepartment of Chemistry and Molecular Biology, Centre for Antibiotic Resistance Research, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0001-6144-2740
Anne FarewellDepartment of Chemistry and Molecular Biology, Centre for Antibiotic Resistance Research, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0002-0841-4908
Natalie VerstraetenCentre of Microbial and Plant Genetics, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0002-9548-4647
Jan MichielsCentre of Microbial and Plant Genetics, KU Leuven, 3001 Leuven, Belgium.
Vlaams Instituut voor Biotechnologie · BECentre National de la Recherche Scientifique · FRUniversity of Gothenburg · SE

Funding

KU Leuven Research Council C16/17/006Research Foundation Flanders G0B0420NTransPred JPIAMR_2016_P006
6 · The paper itself

Abstract

The emergence and dissemination of antibiotic resistance threaten the treatment of common bacterial infections. Resistance genes are often encoded on conjugative elements, which can be horizontally transferred to diverse bacteria. In order to delay conjugative transfer of resistance genes, more information is needed on the genetic determinants promoting conjugation. Here, we focus on which bacterial host factors in the donor assist transfer of conjugative plasmids. We introduced the broad-host-range plasmid pKJK10 into a diverse collection of 113

Indexed as

antibiotic resistancebacterial conjugationconjugation inhibitorsEscherichia coliflow cytometrygenome-wide association studyhorizontal gene transferhost factorsnatural isolatesplasmid

Identifiers

PMID35336183
PMCPMC8954029
OpenAlexW4220717416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.