Evidence map›Paper›PMID 35336032›Full record

ArticlePharmaceutics2022

Tailoring Rational Manufacturing of Extemporaneous Compounding Oral Dosage Formulations with a Low Dose of Minoxidil.

Carlos Torrado-Salmeron, Almudena Laguna, Alicia Guillén, Miguel G Saro, Antonio Matji, Juan J Torrado, Dolores R Serrano

Abstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carlos Torrado-SalmeronDepartment of Pharmaceutics and Food Technology, Complutense University of Madrid, 28240 Madrid, Spain.ORCID 0000-0002-4123-3367
Almudena LagunaDepartment of Pharmaceutics and Food Technology, Complutense University of Madrid, 28240 Madrid, Spain.
Alicia GuillénDepartment of Pharmaceutics and Food Technology, Complutense University of Madrid, 28240 Madrid, Spain.
Miguel G SaroDepartment of Pharmaceutics and Food Technology, Complutense University of Madrid, 28240 Madrid, Spain.
Antonio MatjiDepartment of Pharmaceutics and Food Technology, Complutense University of Madrid, 28240 Madrid, Spain.
Juan J TorradoDepartment of Pharmaceutics and Food Technology, Complutense University of Madrid, 28240 Madrid, Spain.ORCID 0000-0002-7823-1904
Dolores R SerranoDepartment of Pharmaceutics and Food Technology, Complutense University of Madrid, 28240 Madrid, Spain.ORCID 0000-0002-0475-8420

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low amounts of minoxidil in oral dosage forms are commonly prescribed as anti-alopecic pharmacological treatments. Side effects are usually related to individual susceptibility. However, poor drug content and mass uniformity can lead to a potential risk of overdosing, and higher chances to experience side effects. The impacts of four formulation variables on drug content and mass pharmaceutical quality attributes were studied with an experimental design at two levels. The first variable (A) was the particle size of the direct compression microcrystalline cellulose (MCC) used as a diluent (Avicel

Indexed as

capsulecompoundingcontentminoxidilparticle sizetabletuniformity

Identifiers

PMID35336032
PMCPMC8950007

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.