Evidence map›Paper›PMID 35336012›Full record

ArticlePharmaceutics2022

Iron-Gold Nanoflowers: A Promising Tool for Multimodal Imaging and Hyperthermia Therapy.

Evangelia Christou, John R Pearson, Ana M Beltrán, Yilian Fernández-Afonso, Lucía Gutiérrez, Jesús M de la Fuente, Francisco Gámez, María L García-Martín, Carlos Caro

Abstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Materials (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Star-Shaped Magnetic-Plasmonic Au@FeACS applied materials & interfaces · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Evangelia ChristouBIONAND-Centro Andaluz de Nanomedicina y Biotecnología (Junta de Andalucía-Universidad de Málaga), C/Severo Ochoa, 35, 29590 Málaga, Spain.ORCID 0000-0001-9234-481X
John R PearsonBIONAND-Centro Andaluz de Nanomedicina y Biotecnología (Junta de Andalucía-Universidad de Málaga), C/Severo Ochoa, 35, 29590 Málaga, Spain.ORCID 0000-0002-2267-0844
Ana M BeltránDepartamento de Ingeniería y Ciencia de los Materiales y del Transporte, Escuela Politécnica Superior, Universidad de Sevilla, Virgen de Á frica 7, 41011 Sevilla, Spain.ORCID 0000-0003-2599-5908
Yilian Fernández-AfonsoInstituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-0970-1917
Lucía GutiérrezInstituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0003-2366-3598
Jesús M de la FuenteInstituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0003-1081-8482
Francisco GámezDepartamento de Química Física, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0001-6937-9950
María L García-MartínBIONAND-Centro Andaluz de Nanomedicina y Biotecnología (Junta de Andalucía-Universidad de Málaga), C/Severo Ochoa, 35, 29590 Málaga, Spain.ORCID 0000-0002-2257-7682
Carlos CaroBIONAND-Centro Andaluz de Nanomedicina y Biotecnología (Junta de Andalucía-Universidad de Málaga), C/Severo Ochoa, 35, 29590 Málaga, Spain.ORCID 0000-0003-4758-3816

Funding

Regional Ministry of Health of Andalusia OH-0026-2018Regional Ministry of Health of Andalusia PAIDI 2020. P20_00727Spanish Ministry of Economy, Industry and Competitiveness CTQ2017-86655-RSpanish Ministry of Science and Innovation PGC2018-096016-B-I00Spanish Ministry of Science and Innovation PID2020-113108RB-I00Spanish Ministry of Science and Innovation PID2020-118448RB-C21
6 · The paper itself

Abstract

The development of nanoplatforms prepared to perform both multimodal imaging and combined therapies in a single entity is a fast-growing field. These systems are able to improve diagnostic accuracy and therapy success. Multicomponent Nanoparticles (MCNPs), composed of iron oxide and gold, offer new opportunities for Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) diagnosis, as well as combined therapies based on Magnetic Hyperthermia (MH) and Photothermal Therapy (PT). In this work, we describe a new seed-assisted method for the synthesis of Au@Fe Nanoparticles (NPs) with a flower-like structure. For biomedical purposes, Au@Fe NPs were functionalized with a PEGylated ligand, leading to high colloidal stability. Moreover, the as-obtained Au@Fe-PEG NPs exhibited excellent features as both MRI and CT Contrast Agents (CAs), with high r

Indexed as

CTgold–iron nanoparticlesmagnetic hyperthermiaMRImultimodal imagingnanoflowersphotothermal therapy

Identifiers

PMID35336012
PMCPMC8955043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.