Evidence map›Paper›PMID 35335922›Full record

ArticlePharmaceutics2022

Alleviation of Surgery-Induced Osteitis in Sinonasal Cavity by Dexamethasone-Loaded Poly(lactic-

Seung-No Hong, Minjae Kim, Jin-A Park, Minji Kang, Hyunkyung Cha, Sohyun Park, Joon Kon Kim, Jinyoung Pac, Yuju Seo, Sungwhan Kim and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Seung-No HongDepartment of Otolaryngology-Head and Neck Surgery, Seoul National University Boramae Medical Center, 5 Gil 20, Boramae-ro, Dongjak-gu, Seoul 07061, Korea.
Minjae KimDepartment of Chemistry, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul 08826, Korea.
Jin-A ParkDepartment of Otolaryngology-Head and Neck Surgery, Seoul National University Boramae Medical Center, 5 Gil 20, Boramae-ro, Dongjak-gu, Seoul 07061, Korea.
Minji KangDepartment of Chemistry, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul 08826, Korea.
Hyunkyung ChaDepartment of Otolaryngology-Head and Neck Surgery, Seoul National University Boramae Medical Center, 5 Gil 20, Boramae-ro, Dongjak-gu, Seoul 07061, Korea.ORCID 0000-0002-3462-3789
Sohyun ParkDepartment of Chemistry, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul 08826, Korea.
Joon Kon KimDepartment of Otolaryngology-Head and Neck Surgery, Daejeon Eulji Medical Center, Eulji University, Daejeon 35233, Korea.
Jinyoung PacDepartment of Chemistry, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul 08826, Korea.
Yuju SeoDepartment of Otolaryngology-Head and Neck Surgery, Chungnam National University Hospital, Chungnam National University, Daejeon 35015, Korea.
Sungwhan KimDepartment of Chemistry, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul 08826, Korea.
Minju KimDepartment of Otolaryngology-Head and Neck Surgery, Seoul National University Boramae Medical Center, 5 Gil 20, Boramae-ro, Dongjak-gu, Seoul 07061, Korea.ORCID 0000-0003-4612-7624
Dae Woo KimDepartment of Otolaryngology-Head and Neck Surgery, Seoul National University Boramae Medical Center, 5 Gil 20, Boramae-ro, Dongjak-gu, Seoul 07061, Korea.
Yan LeeDepartment of Chemistry, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul 08826, Korea.
Seoul National University · KRChungnam National University Hospital · KREulji University · KR

Funding

Boramae Medical Center 02-2020-7Yangyoung foundation 2021
6 · The paper itself

Abstract

For the treatment of sinus surgery-induced osteitis in chronic rhinosinusitis (CRS), oral or intranasal administration of corticoids is generally used, although it has critical limitations and unavoidable side effects. To overcome these limitations, we designed dexamethasone (Dex)-loaded poly(lactic-

Indexed as

calcium bindingchronic rhinosinusitisdexamethasoneosteitispoly(lactic-co-glycolic acid) (PLGA)sinonasal cavity

Identifiers

PMID35335922
PMCPMC8950508
OpenAlexW4214695149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.