Evidence map›Paper›PMID 35335677›Full record

ReviewPathogens (Basel, Switzerland)2022

Addressing the Data Gaps on Child and Adolescent Tuberculosis.

Sabine Verkuijl, Moorine Penninah Sekadde, Peter J Dodd, Moses Arinaitwe, Silvia S Chiang, Annemieke Brands, Kerri Viney, Charalambos Sismanidis, Helen E Jenkins

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sabine VerkuijlGlobal Tuberculosis Programme, World Health Organization, 1211 Geneva, Switzerland.ORCID 0000-0002-0046-4759
Moorine Penninah SekaddeNational Tuberculosis and Leprosy Programme, Kampala 7025, Uganda.
Peter J DoddSchool of Health and Related Research, University of Sheffield, Sheffield S1 4DA, UK.ORCID 0000-0001-5825-9347
Moses ArinaitweNational Tuberculosis and Leprosy Programme, Kampala 7025, Uganda.
Silvia S ChiangDepartment of Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
Annemieke BrandsGlobal Tuberculosis Programme, World Health Organization, 1211 Geneva, Switzerland.
Kerri VineyGlobal Tuberculosis Programme, World Health Organization, 1211 Geneva, Switzerland.
Charalambos SismanidisGlobal Tuberculosis Programme, World Health Organization, 1211 Geneva, Switzerland.ORCID 0000-0002-5338-3952
Helen E JenkinsDepartment of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.

Funding

Evaluating the tuberculosis epidemic in South Africa using a novel ten-year cohortR01AI152126 · NIAID · WITS HEALTH CONSORTIUM (PTY), LTD · PI JENKINS, HELEN E., SCOTT, LESLEY · 2020 to 2024
$1.6M
Teens on TB Treatment: Predicting Adherence through Clinical Decision AnalysisK01TW010829 · FIC · RHODE ISLAND HOSPITAL · PI CHIANG, SILVIA SHINPEI · 2017 to 2021
$775k
Tracking tuberculosis patients in Ukraine to understand pathways through care and the impact of geographic movementsR03AI164123 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI JENKINS, HELEN E. · 2021 to 2022
$165k
FIC NIH HHS K01 TW010829NIAID NIH HHS L40 AI141492NIAID NIH HHS R03 AI164123NIH HHS R01 AI152126NIH HHS R03 AI164123World Health Organization 001
6 · The paper itself

Abstract

The burden of tuberculosis (TB) among children and young adolescents (<15 years old) is estimated at 1.1 million; however, only 400,000 are treated for TB, indicating a large gap between the number who are cared for and the number estimated to have TB. Accurate data on the burden of pediatric TB is essential to guide action. Despite several improvements in estimating the burden of pediatric TB in the last decade, as well as enhanced data collection efforts, several data gaps remain, both at the global level, but also at the national level where surveillance systems and collaborative research are critical. In this article, we describe recent advances in data collection and burden estimates for TB among children and adolescents, and the remaining gaps. While data collection continues to improve, burden estimates must evolve in parallel, both in terms of their frequency and the methods used. Currently, at the global level, there is a focus on age-disaggregation of TB notifications, the collection of data on TB-HIV, multi-drug resistant (MDR)-TB and treatment outcomes, as well as estimates of the disease burden. Additional data from national surveillance systems or research projects on TB meningitis, as well as other forms of extra-pulmonary TB, would be useful. We must capitalize on the current momentum in child and adolescent TB to close the remaining data gaps for these age groups to better understand the epidemic and further reduce morbidity and mortality due to TB.

Indexed as

tuberculosis

Identifiers

PMID35335677
PMCPMC8955570

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.