Evidence map›Paper›PMID 35335664›Full record

ArticlePathogens (Basel, Switzerland)2022

Performance of Five Metagenomic Classifiers for Virus Pathogen Detection Using Respiratory Samples from a Clinical Cohort.

Ellen C Carbo, Igor A Sidorov, Anneloes L van Rijn-Klink, Nikos Pappas, Sander van Boheemen, Hailiang Mei, Pieter S Hiemstra, Tomas M Eagan, Eric C J Claas, Aloys C M Kroes and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ellen C CarboDepartment of Medical Microbiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Igor A SidorovDepartment of Medical Microbiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Anneloes L van Rijn-KlinkDepartment of Medical Microbiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Nikos PappasSequencing Analysis Support Core, Department of Biomedical Data Sciences, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Sander van BoheemenDepartment of Medical Microbiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Hailiang MeiSequencing Analysis Support Core, Department of Biomedical Data Sciences, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0003-1781-5508
Pieter S HiemstraDepartment of Pulmonology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0002-0238-5982
Tomas M EaganDepartment of Thoracic Medicine, Haukeland University Hospital, 5021 Bergen, Norway.
Eric C J ClaasDepartment of Medical Microbiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Aloys C M KroesDepartment of Medical Microbiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Jutte J C de VriesDepartment of Medical Microbiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Leiden University Medical Center · NLHaukeland University Hospital · NOUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral metagenomics is increasingly applied in clinical diagnostic settings for detection of pathogenic viruses. While several benchmarking studies have been published on the use of metagenomic classifiers for abundance and diversity profiling of bacterial populations, studies on the comparative performance of the classifiers for virus pathogen detection are scarce. In this study, metagenomic data sets (

Indexed as

bioinformaticsnext-generation sequencingpathogen detectionviral metagenomics

Identifiers

PMID35335664
PMCPMC8953373
OpenAlexW4220837069

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.