Evidence map›Paper›PMID 35335645›Full record

ArticlePathogens (Basel, Switzerland)2022

Human Polymorphonuclear Cells Support Zika Virus to Cross Endothelial Monolayer and Access Bloodstream.

Claudia Gandolfo, Chiara Terrosi, Shibily Prathyumnan, Gabriele Anichini, Gianni Gori Savellini, Giuseppe Morgante, Maria Grazia Cusi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Claudia GandolfoDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-2174-0713
Chiara TerrosiDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Shibily PrathyumnanDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Gabriele AnichiniDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0001-9895-2488
Gianni Gori SavelliniDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-2287-9258
Giuseppe MorganteDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0001-5024-2321
Maria Grazia CusiDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0001-8869-8164
University of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid spread of new outbreaks of human infection caused by Zika virus (ZIKV) has raised many global concerns since 2016. Despite the increasing knowledge of this virus, data on the pathogenesis of ZIKV are still missing. In particular, it is still unknown how the virus crosses the endothelial monolayer and gets access to the bloodstream. In the present work, we used human umbilical vein endothelial cells (HUVECs) as a model to study ZIKV infection

Indexed as

cell junctionsendothelial monolayerHUVECsviral infectionZika virus

Identifiers

PMID35335645
PMCPMC8955922
OpenAlexW4220743989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.