Evidence map›Paper›PMID 35335637›Full record

ArticlePathogens (Basel, Switzerland)2022

Incidence, Persistence, and Clearance of Anal Human Papillomavirus among Men Who Have Sex with Men in China: An Observational Cohort Study.

Yiguo Zhou, Xinyi Zhou, Yi-Fan Lin, Ganfeng Luo, Yong Lu, Zhenyu Wang, Peiyang Li, Zhenzhou Luo, Xiaojun Meng, Tian Tian and 3 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Yiguo ZhouSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.ORCID 0000-0002-2172-4396
Xinyi ZhouSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.
Yi-Fan LinSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.
Ganfeng LuoSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.
Yong LuSchool of Public Health, Sun Yat-sen University, Guangzhou 510006, China.
Zhenyu WangSchool of Public Health, Sun Yat-sen University, Guangzhou 510006, China.
Peiyang LiSchool of Public Health, Sun Yat-sen University, Guangzhou 510006, China.
Zhenzhou LuoShenzhen Nanshan Center for Chronic Disease Control, Shenzhen 518000, China.
Xiaojun MengWuxi Municipal Centre for Disease Control and Prevention, Wuxi 214023, China.
Tian TianSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.
Leiwen FuSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.
Jianghong DaiSchool of Public Health, Xinjiang Medical University, Urumqi 830011, China.
Huachun ZouSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.ORCID 0000-0002-8161-7576
Sun Yat-sen University · CNGuiyang Medical University · CNNanjing Municipal Center for Disease Control And Prevention · CNShenzhen Nanshan Center for Chronic Disease Control · CNXinjiang Medical University · CN

Funding

Natural Science Foundation of China Excellent Young Scientists Fund 82022064Natural Science Foundation of China International/Regional Research Collaboration Project 72061137001Special Support Plan for High-Level Talents of Guangdong Province 2019TQ05Y230
6 · The paper itself

Abstract

(1) Background: We conducted a prospective observational cohort study to measure incidence, persistence, and clearance of anal human papillomavirus (HPV) among men who have sex with men (MSM) in China. (2) Methods: MSM were recruited in Guangzhou, Shenzhen and Wuxi, China in 2017. A tablet-based questionnaire was used to collect sociodemographic and behavioral characteristics. An anal brush sample was collected for HPV testing and genotyping. Participants were followed up 12 months after enrolment. (3) Results: A total of 196 participants completed two HPV tests with a median age of 27.3 (interquartile range (IQR) 24.0-32.8) years. Rate of incidence, persistence, and clearance for HPV among MSM were 31.3 (95% confidence interval (CI) 24.7-39.2), 47.9 (36.8-61.3), and 122.5 (104.3-143.0) per 1000 person months (pm), respectively. HPV 16 (4.1/1000 pm) had the highest incidence rate, and HPV 6 (47.4/1000 pm) had the highest persistence rate. Having lower education and engaging in receptive anal intercourse were potential risk factors of HPV incidence. A higher incidence rate was observed among younger MSM. (4) Conclusions: The high incidence and low clearance of anal HPV highlight the necessity of HPV vaccination among MSM. Further studies are needed to clarify the HPV dynamics at multiple anatomical sites and the burden of HPV-related diseases among MSM.

Indexed as

clearancehuman papillomavirusincidencemen who have sex with menpersistence

Identifiers

PMID35335637
PMCPMC8949987
OpenAlexW4214935188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.