Evidence map›Paper›PMID 35335625›Full record

ArticlePathogens (Basel, Switzerland)2022

Impact of Sainfoin (

Michaela Komáromyová, Daniel Petrič, Katarína Kucková, Dominika Batťányi, Michal Babják, Michaela Urda Dolinská, Alžbeta Königová, Daniel Barčák, Emília Dvorožňáková, Klaudia Čobanová and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Michaela KomáromyováInstitute of Parasitology, Slovak Academy of Sciences, Hlinkova 3, 040 01 Košice, Slovakia.
Daniel PetričUniversity of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 041 81 Košice, Slovakia.
Katarína KuckováUniversity of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 041 81 Košice, Slovakia.ORCID 0000-0002-8373-8988
Dominika BatťányiCentre of Biosciences of Slovak Academy of Sciences, Institute of Animal Physiology, Šoltésovej 4-6, 040 01 Košice, Slovakia.ORCID 0000-0002-9070-0558
Michal BabjákInstitute of Parasitology, Slovak Academy of Sciences, Hlinkova 3, 040 01 Košice, Slovakia.ORCID 0000-0002-5564-5960
Michaela Urda DolinskáInstitute of Parasitology, Slovak Academy of Sciences, Hlinkova 3, 040 01 Košice, Slovakia.ORCID 0000-0002-7194-555X
Alžbeta KönigováInstitute of Parasitology, Slovak Academy of Sciences, Hlinkova 3, 040 01 Košice, Slovakia.ORCID 0000-0002-0479-3445
Daniel BarčákInstitute of Parasitology, Slovak Academy of Sciences, Hlinkova 3, 040 01 Košice, Slovakia.ORCID 0000-0002-5975-0899
Emília DvorožňákováInstitute of Parasitology, Slovak Academy of Sciences, Hlinkova 3, 040 01 Košice, Slovakia.
Klaudia ČobanováCentre of Biosciences of Slovak Academy of Sciences, Institute of Animal Physiology, Šoltésovej 4-6, 040 01 Košice, Slovakia.ORCID 0000-0001-5842-1965
Zora VáradyováCentre of Biosciences of Slovak Academy of Sciences, Institute of Animal Physiology, Šoltésovej 4-6, 040 01 Košice, Slovakia.ORCID 0000-0003-3675-8641
Marián VáradyInstitute of Parasitology, Slovak Academy of Sciences, Hlinkova 3, 040 01 Košice, Slovakia.ORCID 0000-0001-6589-8219
Slovak Academy of Sciences · SK

Funding

SAS Programme for PhD students'grants DoktoGrant APP0162Slovak Research and Development Agency APVV 18-0131
6 · The paper itself

Abstract

Our study analyzed the parasitological status, antibody responses, and antioxidant parameters of lambs experimentally infected with a gastrointestinal nematode during the consumption of sainfoin pellets (SFPs) for 14 d. Twenty-four lambs infected with Haemonchus contortus were separated into two groups: untreated animals (control) and animals treated with SFPs (600 g dry matter/d). SFP treatment began on day (D) 30 post-infection. The number of eggs per gram (EPG) of feces was quantified on D18, D23, D26, D30, D33, D37, D40, and D44. The mean reductions in EPG on D40 and D44 were 33.6 and 36.7%, respectively. The number of abomasal worms was lower for the SFP than the control group (p < 0.05). SFP treatment did not significantly affect either the total or the local antibody response (p > 0.05). The blood activity of glutathione peroxidase was affected by the treatment (p < 0.022). Adult worms were selected for scanning electron microscopy after necropsy, but surface structures of adult H. contortus females did not differ between the groups. The treatment of lambs with SFPs directly affected the dynamics of infection, probably indirectly by mobilizing the antioxidant defensive system and antibody response thus improving animal resistance.

Indexed as

abomasal adult wormsantibody responseantioxidant statusegg hatch testfecal egg countsscanning electron microscopy

Identifiers

PMID35335625
PMCPMC8954349
OpenAlexW4214693115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.