Evidence map›Paper›PMID 35335590›Full record

ReviewPolymers2022

Polyacrylic Acid Nanoplatforms: Antimicrobial, Tissue Engineering, and Cancer Theranostic Applications.

Hassan Arkaban, Mahmood Barani, Majid Reza Akbarizadeh, Narendra Pal Singh Chauhan, Sapana Jadoun, Maryam Dehghani Soltani, Payam Zarrintaj

Abstract readReview
In one paragraph

Review in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Biodegradable Adhesive Systems for Bio-Integrated Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Fabrication of PAA-RSC advances · 2025
    Article
  16. Article
  17. Review
  18. Chelation-induced anti-Ostwald ripening: Ultrafine bismuth nanocrystals for ultrastable aqueous sodium storage.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  19. Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hassan ArkabanDepartment of Chemistry, University of Isfahan, Isfahan 8174673441, Iran.ORCID 0000-0002-8859-4290
Mahmood BaraniMedical Mycology and Bacteriology Research Center, Kerman University of Medical Sciences, Kerman 7616913555, Iran.ORCID 0000-0002-1711-2522
Majid Reza AkbarizadehDepartment of Pediatric, Amir Al Momenin Hospital, Zabol University of Medical Sciences, Zabol 9861663335, Iran.
Narendra Pal Singh ChauhanDepartment of Chemistry, Faculty of Science, Bhupal Nobles's University, Udaipur 313002, Rajasthan, India.ORCID 0000-0003-3241-7460
Sapana JadounDepartment of Analytical and Inorganic Chemistry, Faculty of Sciences, University of Concepcion, Edmundo Larenas 129, Concepcion 4070371, Chile.ORCID 0000-0002-3572-7934
Maryam Dehghani SoltaniDepartment of Chemistry, Faculty of Science, Yazd University, Yazd 8915818411, Iran.
Payam ZarrintajSchool of Chemical Engineering, Oklahoma State University, 420 Engineering North, Stillwater, OK 74078, USA.ORCID 0000-0002-1609-7519

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyacrylic acid (PAA) is a non-toxic, biocompatible, and biodegradable polymer that gained lots of interest in recent years. PAA nano-derivatives can be obtained by chemical modification of carboxyl groups with superior chemical properties in comparison to unmodified PAA. For example, nano-particles produced from PAA derivatives can be used to deliver drugs due to their stability and biocompatibility. PAA and its nanoconjugates could also be regarded as stimuli-responsive platforms that make them ideal for drug delivery and antimicrobial applications. These properties make PAA a good candidate for conventional and novel drug carrier systems. Here, we started with synthesis approaches, structure characteristics, and other architectures of PAA nanoplatforms. Then, different conjugations of PAA/nanostructures and their potential in various fields of nanomedicine such as antimicrobial, anticancer, imaging, biosensor, and tissue engineering were discussed. Finally, biocompatibility and challenges of PAA nanoplatforms were highlighted. This review will provide fundamental knowledge and current information connected to the PAA nanoplatforms and their applications in biological fields for a broad audience of researchers, engineers, and newcomers. In this light, PAA nanoplatforms could have great potential for the research and development of new nano vaccines and nano drugs in the future.

Indexed as

anticancerantimicrobialbiosensingpolyacrylic acid (PAA)polymerizationssynthesize

Identifiers

PMID35335590
PMCPMC8948866

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.