Evidence map›Paper›PMID 35335396›Full record

ArticleMolecules (Basel, Switzerland)2022

Automated Synthesis of

Anton Amadeus Hörmann, Elisabeth Plhak, Maximilian Klingler, Christine Rangger, Joachim Pfister, Gert Schwach, Herbert Kvaternik, Elisabeth von Guggenberg

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Towards Optimal AutomatedJournal of labelled compounds & radiopharmaceuticals · 2024
    Article
  3. Article
  4. Article
  5. Automated Synthesis of [Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Anton Amadeus HörmannDepartment of Nuclear Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Elisabeth PlhakDepartment of Pharmaceutical Chemistry, Institute of Pharmaceutical Sciences, University of Graz, 8010 Graz, Austria.
Maximilian KlinglerDepartment of Nuclear Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Christine RanggerDepartment of Nuclear Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-1167-9779
Joachim PfisterDepartment of Nuclear Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-5357-126X
Gert SchwachDivision of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria.
Herbert KvaternikDepartment of Radiology, Division of Nuclear Medicine, Medical University of Graz, 8036 Graz, Austria.
Elisabeth von GuggenbergDepartment of Nuclear Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-4944-4705
Innsbruck Medical University · ATMedical University of Graz · ATUniversity of Graz · AT

Funding

Austrian Science Fund FWF P 27844FWF Austrian Science Fund P 27844
6 · The paper itself

Abstract

The new minigastrin analog DOTA-MGS8 targeting the cholecystokinin-2 receptor (CCK2R) used in this study displays the combination of two site-specific modifications within the C-terminal receptor binding sequence together with an additional N-terminal amino acid substitution preventing fast metabolic degradation. Within this study, the preparation of

Indexed as

Gallium RadioisotopesReceptor, Cholecystokinin BAnimalsCell Line, TumorHeterocyclic Compounds, 1-RingHumansMiceMice, NudeRatsTissue Distribution1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidGallium RadioisotopesHeterocyclic Compounds, 1-RingReceptor, Cholecystokinin Bautomated synthesischolecystokinin-2 receptorminigastrinmolecular imagingradiometals

Identifiers

PMID35335396
PMCPMC8949806
OpenAlexW4221056398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.