Evidence map›Paper›PMID 35335393›Full record

ReviewMolecules (Basel, Switzerland)2022

Chemistry, Biosynthesis and Pharmacology of Sarsasapogenin: A Potential Natural Steroid Molecule for New Drug Design, Development and Therapy.

Nur Hanisah Mustafa, Mahendran Sekar, Shivkanya Fuloria, M Yasmin Begum, Siew Hua Gan, Nur Najihah Izzati Mat Rani, Subban Ravi, Kumarappan Chidambaram, Vetriselvan Subramaniyan, Kathiresan V Sathasivam and 6 more

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

  1. Sarsasapogenin Preserves Podocyte Integrity and Attenuates Renal Injury in Experimental IgA Nephropathy.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 4 countries.

Nur Hanisah MustafaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh 30450, Malaysia.
Mahendran SekarDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh 30450, Malaysia.ORCID 0000-0002-3022-6137
Shivkanya FuloriaFaculty of Pharmacy, AIMST University, Bedong 08100, Malaysia.
M Yasmin BegumDepartment of Pharmaceutics, College of Pharmacy, King Khalid University, Abha 61421, Saudi Arabia.ORCID 0000-0002-1871-8585
Siew Hua GanSchool of Pharmacy, Monash University Malaysia, Bandar Sunway, Kuala Lumpur 47500, Malaysia.ORCID 0000-0001-6470-3651
Nur Najihah Izzati Mat RaniFaculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh 30450, Malaysia.ORCID 0000-0001-6342-807X
Subban RaviDepartment of Chemistry, Karpagam Academy of Higher Education, Coimbatore 641021, Tamil Nadu, India.
Kumarappan ChidambaramDepartment of Pharmacology, College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia.ORCID 0000-0002-7981-4562
Vetriselvan SubramaniyanFaculty of Medicine, Bioscience and Nursing, MAHSA University, Jalan SP 2, Bandar Saujana Putra, Jenjarom 42610, Malaysia.ORCID 0000-0002-9629-9494
Kathiresan V SathasivamFaculty of Applied Sciences, AIMST University, Bedong, Sungai Petani 08100, Malaysia.
Srikanth JeyabalanDepartment of Pharmacology, Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai 600116, Tamil Nadu, India.ORCID 0000-0003-3514-7654
Subasini UthirapathyFaculty of Pharmacy, Tishk International University, Erbil 44001, Kurdistan Region, Iraq.ORCID 0000-0003-1250-388X
Sivasankaran PonnusankarDepartment of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty 643001, Tamil Nadu, India.ORCID 0000-0001-5589-090X
Pei Teng LumDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh 30450, Malaysia.
Vijay BhallaSGT College of Pharmacy, SGT University, Gurugram 122505, Haryana, India.
Neeraj Kumar FuloriaFaculty of Pharmacy, AIMST University, Bedong 08100, Malaysia.
University of Kuala Lumpur · MYAIMST University · MYKing Khalid University · SAJSS Academy of Higher Education and Research · INKarpagam Academy of Higher Education · INMahsa University · MYMonash University Malaysia · MYShree Guru Gobind Singh Tricentenary University · INSri Ramachandra Institute of Higher Education and Research · INTishk International University · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarsasapogenin is a natural steroidal sapogenin molecule obtained mainly from

Indexed as

AnemarrhenaSpirostansDrug DesignsarsasapogeninSpirostansbiosynthesisdrug developmentpharmacologyphytochemistrysarsasapogeninsteroid

Identifiers

PMID35335393
PMCPMC8955086
OpenAlexW4220759367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.