Evidence map›Paper›PMID 35335386›Full record

ArticleMolecules (Basel, Switzerland)2022

Structure-Based Molecular Networking for the Discovery of Anti-HBV Compounds from

Tao Wu, Xin-Jian Yan, Tian-Rong Yang, Yun-Fen Wang, Jing-Yi He, Yang Feng, Li-Hua Su, Hao Chen, Min Xu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Tao WuCenter for Pharmaceutical Sciences, Faculty of Life Science and Technology, Chenggong Campus, Kunming University of Science and Technology, Kunming 650500, China.
Xin-Jian YanCenter for Pharmaceutical Sciences, Faculty of Life Science and Technology, Chenggong Campus, Kunming University of Science and Technology, Kunming 650500, China.
Tian-Rong YangCenter for Pharmaceutical Sciences, Faculty of Life Science and Technology, Chenggong Campus, Kunming University of Science and Technology, Kunming 650500, China.
Yun-Fen WangCenter for Pharmaceutical Sciences, Faculty of Life Science and Technology, Chenggong Campus, Kunming University of Science and Technology, Kunming 650500, China.
Jing-Yi HeCenter for Pharmaceutical Sciences, Faculty of Life Science and Technology, Chenggong Campus, Kunming University of Science and Technology, Kunming 650500, China.
Yang FengCenter for Pharmaceutical Sciences, Faculty of Life Science and Technology, Chenggong Campus, Kunming University of Science and Technology, Kunming 650500, China.
Li-Hua SuCenter for Pharmaceutical Sciences, Faculty of Life Science and Technology, Chenggong Campus, Kunming University of Science and Technology, Kunming 650500, China.
Hao ChenCenter for Pharmaceutical Sciences, Faculty of Life Science and Technology, Chenggong Campus, Kunming University of Science and Technology, Kunming 650500, China.
Min XuCenter for Pharmaceutical Sciences, Faculty of Life Science and Technology, Chenggong Campus, Kunming University of Science and Technology, Kunming 650500, China.ORCID 0000-0001-6654-8878
Kunming University of Science and Technology · CN

Funding

National Natural Science Foundation of China 31960093National Natural Science Foundation of China 81973210Ronald J Quinn AM Academician Workstation 2019IC003
6 · The paper itself

Abstract

It is a crucial to find target compounds in natural product research. This study presents a concept of structure-guided isolation to find candidate active molecules from herbs. We establish a process of anti-viral sesquiterpene networking. An analysis of the networking suggested that new anti-HBV sesquiterpene may be attributable to eudesmane-, guaiane-, cadinane-, germacane- and bisabolane-type sesquiterpenes. In order to evaluate the efficiency of the structure-based molecular networking, ethanol extract of

Indexed as

SaussureaSesquiterpenesHepatitis B Surface AntigensHepatitis B virusPlant ExtractsHepatitis B Surface AntigensPlant ExtractsSesquiterpenesanti-HBV activitySaussurea lappasesquiterpenesstructure-guided isolation

Identifiers

PMID35335386
PMCPMC8955460
OpenAlexW4220894923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.