ArticleMolecules (Basel, Switzerland)2022
Antimicrobial and Cytotoxic Activity of Novel Imidazolium-Based Ionic Liquids.
Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Synthesis and Auxin-like Activity of Halogenated Alkylphenoxyacetic Acids.International journal of molecular sciences · 2026Article
- Ionic Liquids as Antibacterial and Drug Delivery Agents: How Cationic Amphiphilic Structure Controls Morphology Changes in Lipid Bilayers and Penetration Mechanism.The journal of physical chemistry. B · 2026Article
- Ionic Liquid-Enabled Drug Delivery Systems: Benefits, Limitations, and Future Perspectives.Pharmaceutics · 2026Review
- L-Glycine and L-leucine derived multifunctional ionic liquids for potential antibacterial applications: in-vitro and in-silico studies.BMC chemistry · 2025Article
- Antibacterial Activity of Bis(4-aminopyridinium) Compounds for Their Potential Use as Disinfectants.Molecules (Basel, Switzerland) · 2025Article
- A convergence of synthesis and antimicrobial research: imidazolium based dicationic ionic liquids.BMC chemistry · 2025Article
- Surface-Active Amidequats with an Alkoxymethyl Substituent: Synthesis, Analysis, and Preliminary Evaluation as Potential Emulsifiers and Substitutes for Conventional Surfactants.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Article
- Surface-Active Ionic Liquids and Surface-Active Quaternary Ammonium Salts from Synthesis, Characterization to Antimicrobial Properties.Molecules (Basel, Switzerland) · 2024Article
- Article
- New Potential Agents for Malignant Melanoma Treatment-Most Recent Studies 2020-2022.International journal of molecular sciences · 2022Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
In this study, a series of 10 novel 1-methyl-3-octyloxymethylimidazolium derivatives carrying various anionic moieties (4-hydroxybenzenesulfonate, benzenesulfonate, carvacroloxyacetate, chloride, formate, propionate, thymoloxyacetate, vanillinoxyacetate, eugenoloxyacetate and trimethylacetate) were synthesized. Compounds were tested for their antimicrobial activity against six microbe strains (Staph-ylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Enterococcus faecalis, and Candida albicans), cytotoxic activity against the mouse melanoma cell line (B16 F10), and surface active properties. All synthesized compounds exhibited antimicrobial activity (expressed as minimum inhibitory concentration; in range of 0.10-27.82 mM/L), especially against Gram-positive bacteria and fungi. In addition, all compounds demonstrated cytotoxicity on B16 F10 cells (IC50 values 0.0101-0.0197 mM/L). Surface properties defined as CMC values, ranged from 0.72 to 32.35 mmol L-1. The obtained results provide an insight into the promising activity of a novel group of quaternary imidazolium derivatives having ionic liquid properties. The most potent compounds, containing a thymoloxyacetate and eugenoloxyacetate moiety, could be candidates for new antimicrobial agents or surfactants.
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Registered trials
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