ArticleMolecules (Basel, Switzerland)2022
MXene-AuNP-Based Electrochemical Aptasensor for Ultra-Sensitive Detection of Chloramphenicol in Honey.
Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Ultrasensitive electrochemical biosensor based on MXene quantum dots for prostate cancer biomarker detection.Scientific reports · 2025Article
- A simple self-assembly aptasensor for ultrasensitive detection of kanamycin based on carbon dots and TiRSC advances · 2025Article
- Point-of-care testing device platform for the determination of creatinine on an enzyme@CS/PB/MXene@AuNP-based screen-printed carbon electrode.Mikrochimica acta · 2024Article
- Few Layer TiMolecules (Basel, Switzerland) · 2023Article
- Recent Advances in Electrochemical Biosensors for Food Control.Micromachines · 2023Review
- Bio-Tailored Sensing at the Nanoscale: Biochemical Aspects and Applications.Sensors (Basel, Switzerland) · 2023Review
- Review
- Nitrogen-Doped Porous MXene (TiMolecules (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
A simple and label-free electrochemical aptasensor was developed for ultra-sensitive determination of chloramphenicol (CAP) based on a 2D transition of metal carbides (MXene) loaded with gold nanoparticles (AuNPs). The embedded AuNPs not only inhibit the aggregation of MXene sheets, but also improve the quantity of active sites and electronic conductivity. The aptamers (Apts) were able to immobilize on the MXene-AuNP modified electrode surface through Au-S interaction. Upon specifically binding with CAP with high affinity, the CAP-Apt complexes produced low conductivity on the aptasensor surface, leading to a decreased electrochemical signal. The resulting current change was quantitatively correlated with CAP concentration. Under optimized experimental conditions, the constructed aptasensor exhibited a good linear relationship within a wide range of 0.0001-10 nM and with a low detection limit of 0.03 pM for CAP. Moreover, the developed aptasensor has been applied to the determination of CAP concentration in honey samples with satisfactory results.
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Registered trials
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