Evidence map›Paper›PMID 35335126›Full record

ArticleMolecules (Basel, Switzerland)2022

Botanically-Derived Δ

John-Mark Fitzpatrick, Becky Hackett, Lisa Costelloe, William Hind, Eric J Downer

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

John-Mark FitzpatrickDiscipline of Physiology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, D02 R590 Dublin, Ireland.
Becky HackettDiscipline of Physiology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, D02 R590 Dublin, Ireland.
Lisa CostelloeDepartment of Neurology, Beaumont Hospital, D09 V2N0 Dublin, Ireland.
William HindGW Research Ltd., Sovereign House, Vision Park, Histon CB24 9BZ, UK.
Eric J DownerDiscipline of Physiology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, D02 R590 Dublin, Ireland.ORCID 0000-0002-6012-2291
Trinity College Dublin · IEBeaumont Hospital · IEGW Pharmaceuticals (United Kingdom) · GB

Funding

GW Research Ltd. GW Research Ltd.Irish Research Council EPSPG/2015/131Trinity College Dublin Provosts Project Award
6 · The paper itself

Abstract

The innate immune response to bacterial and viral molecules involves the coordinated production of cytokines, chemokines, and type I interferons (IFNs), which is orchestrated by toll-like receptors (TLRs). TLRs, and their intracellular signalling intermediates, are closely associated with multiple sclerosis (MS) pathogenesis. Recent data from our laboratory reported that the plant-derived cannabinoids, Δ

Indexed as

CannabidiolMultiple SclerosisDronabinolHumansLeukocytes, MononuclearToll-Like Receptor 3Toll-Like Receptor 4CannabidiolDronabinolTLR3 protein, humanTLR4 protein, humanToll-Like Receptor 3Toll-Like Receptor 4cannabinoidsinflammationinnate immunitymultiple sclerosisPBMCTLRs

Identifiers

PMID35335126
PMCPMC8951523
OpenAlexW4220701533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.