ArticleVaccines2022
An Outbreak of Equine Herpesvirus-4 in an Ecological Donkey Milk Farm in Romania.
Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- A Comparative Review of Donkey Genetic Resources, Production Traits, and Industrial Utilization: Perspectives from China and Globally.Animals : an open access journal from MDPI · 2025Review
- Equine Herpesvirus Infections: Treatment Progress and Challenges in Horses and Donkeys.Veterinary sciences · 2025Review
- A multiplex real-time PCR assay for detection of equid herpesvirus 1 and 4.Scientific reports · 2025Article
- Phytogenic and Nutritional Strategies to Improve Milk Production and Microbiological Quality in Lactating Donkeys.Animals : an open access journal from MDPI · 2025Article
- Development and Preclinical Evaluation of a Lyophilized Vaccine Against Equine Herpesvirus Type 4 (EHV-4).Vaccines · 2025Article
- Molecular and Serological Investigation of Equine Herpesvirus Type 1 (EHV-1) and Type 4 (EHV-4) in Horses In Ibagué, Tolima.Veterinary medicine international · 2025Article
- Reproductive Disorders in Donkeys: Current Evidence and Update.Animals : an open access journal from MDPI · 2024Review
- An Overview of Infectious and Non-Infectious Causes of Pregnancy Losses in Equine.Animals : an open access journal from MDPI · 2024Review
- Epidemiological and Phylogeographic Study of Equid Herpesviruses in Tunisia.Pathogens (Basel, Switzerland) · 2022Article
- Frequency of Detection and Prevalence Factors Associated with Common Respiratory Pathogens in Equids with Acute Onset of Fever and/or Respiratory Signs (2008-2021).Pathogens (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Equine herpesviruses are important pathogens causing significant economic loss in equine and asinine populations. EHV-1/4 strains are mainly associated with respiratory distress. The aim of this study is to report the first EHV 4-associated respiratory disease in donkeys in Romania. Thirty-seven of three hundred jennies in an ecological donkey farm in southwest Romania started initially showing signs of severe upper respiratory tract disease, with ten concomitant late abortions/neonatal deaths and three neurological cases. There were nine fatalities. Pathological examination was performed, and samples were collected for Real-Time PCR analysis and histology. In addition, serum samples from 28 individuals with respiratory symptoms were collected and tested using indirect ELISA. RT-PCR identified the EHV-4 strain. Acute, diffuse necrotizing bronchointerstitial pneumonia with occasional intraepithelial intranuclear viral inclusion bodies was identified. Additionally, EHV-1/4-specific antibodies were found in 15 of the 28 sampled animals. Few studies on donkeys and herpesviruses have been published, and this is the first reported case of EHV-4 outbreak in Romania. There is a need for more extensive seroprevalence studies as, currently, the status of EHV-4 infection in donkeys in Romania is unknown.
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