Evidence map›Paper›PMID 35335090›Full record

ArticleVaccines2022

Seroprevalence against Diphtheria in Pregnant Women and Newborns in Colombia: New Arguments to Promote Maternal Immunization.

Laura María Rivera-Santamaría, Doracelly Hincapié-Palacio, Jesús Ochoa, Felipe Vargas-Restrepo, Marta C Ospina, Seti Buitrago-Giraldo

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Serological evaluation of immunity againstHuman vaccines & immunotherapeutics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Laura María Rivera-Santamaría"Hector Abad Gómez" National Faculty of Public Health, Universidad de Antioquia UdeA, Medellin 050010, Colombia.ORCID 0000-0003-1153-0763
Doracelly Hincapié-Palacio"Hector Abad Gómez" National Faculty of Public Health, Universidad de Antioquia UdeA, Medellin 050010, Colombia.
Jesús Ochoa"Hector Abad Gómez" National Faculty of Public Health, Universidad de Antioquia UdeA, Medellin 050010, Colombia.ORCID 0000-0001-9132-2328
Felipe Vargas-Restrepo"Hector Abad Gómez" National Faculty of Public Health, Universidad de Antioquia UdeA, Medellin 050010, Colombia.ORCID 0000-0002-4371-2257
Marta C OspinaLaboratory of Public Health of the Regional Secretariat of Health and Social Protection of Antioquia, Medellin 050010, Colombia.
Seti Buitrago-GiraldoLaboratory of Public Health of the Regional Secretariat of Health and Social Protection of Antioquia, Medellin 050010, Colombia.
Universidad de Antioquia · COMinistry of Health and Social Protection · CO

Funding

Colciencias 699-2018
6 · The paper itself

Abstract

The tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine is recommended during pregnancy for neonatal protection against pertussis, although little is known of the protection it provides against diphtheria. The work used a cross-sectional design to estimate seroprevalence against diphtheria in 805 pregnant women with ≥37 gestation weeks and their newborns whose deliveries were attended in eight hospitals randomly chosen from a subregion of Antioquia, Colombia and to explore factors related with maternal protection. Levels of IgG antibodies were determined by using a commercial enzyme-linked immunosorbent assay test. Placental transfer of antibodies and crude and adjusted prevalence ratio (aPR) were analyzed to describe factors related with maternal protection against diphtheria. Protection against diphtheria was observed in 91.7% (95% CI 90.3-93.0) of the pregnant women and 93.1% (95% CI 91.7-94.4) of newborns, whose antibody levels were positively correlated (Spearman's r = 0.769;

Indexed as

Colombiadiphtheria-tetanus-acellular pertussis vaccinesimmunizationseroepidemiological studies

Identifiers

PMID35335090
PMCPMC8955344
OpenAlexW4220735666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.