Evidence map›Paper›PMID 35335046›Full record

ReviewVaccines2022

Vaccines Against COVID-19: A Review.

Carlos U Torres-Estrella, María Del Rocío Reyes-Montes, Esperanza Duarte-Escalante, Mónica Sierra Martínez, María Guadalupe Frías-De-León, Gustavo Acosta-Altamirano

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Design of cationic ionizable lipids for the delivery of therapeutic nucleic acids.Molecular therapy. Methods & clinical development · 2025
    Review
  2. Vaccination in dermatology 2025: Update considering current recommendations of the German Standing Committee on Vaccination.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. SARS-CoV-2 in brief: from virus to prevention.Osong public health and research perspectives · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Carlos U Torres-EstrellaHospital Regional de Alta Especialidad de Ixtapaluca, Ciudad de México PC 56530, Mexico.ORCID 0000-0003-4525-7734
María Del Rocío Reyes-MontesDepartamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Ciudad de México PC 04510, Mexico.ORCID 0000-0002-3866-9995
Esperanza Duarte-EscalanteDepartamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Ciudad de México PC 04510, Mexico.ORCID 0000-0002-6315-7860
Mónica Sierra MartínezHospital Regional de Alta Especialidad de Ixtapaluca, Ciudad de México PC 56530, Mexico.
María Guadalupe Frías-De-LeónHospital Regional de Alta Especialidad de Ixtapaluca, Ciudad de México PC 56530, Mexico.ORCID 0000-0002-3160-8698
Gustavo Acosta-AltamiranoHospital Regional de Alta Especialidad de Ixtapaluca, Ciudad de México PC 56530, Mexico.
Hospital Regional de Alta Especialidad del Bajío · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a result of the COVID-19 pandemic, various joint efforts have been made to support the creation of vaccines. Different projects have been under development, of which some are in the clinical evaluation stage and others in are in phase III with positive results. The aim of this paper was to describe the current situation of the development and production of vaccines available to the population to facilitate future research and continue developing and proposing ideas for the benefit of the population. So, we carried out a systematic review using databases such as PubMed, ScienceDirect, SciELO, and MEDLINE, including keywords such as "vaccines," "COVID-19," and "SARS-CoV-2". We reviewed the development and production of the anti-COVID vaccine and its different platforms, the background leading to the massive development of these substances, and the most basic immune aspects for a better understanding of their physiological activity and the immune response in those who receive the vaccine. We also analyzed immunization effects in populations with any medical or physiological conditions (such as immunosuppression, people with comorbidities, and pregnancy), as well as the response to immunization with heterologous vaccines and the hybrid immunity (the combination of natural immunity to SARS-CoV-2 with immunity generated by the vaccine). Likewise, we address the current situation in Mexico and its role in managing the vaccination process against SARS-CoV-2 at the national and international levels. There are still many clinical and molecular aspects to be described, such as the duration of active immunity and the development of immunological memory, to mention some of the most important ones. However, due to the short time since the global vaccination roll-out and that it has been progressive (not counting children and people with medical conditions), it is premature to say whether a second vaccination schedule will be necessary for the near future. Thus, it is essential to continue with health measures.

Indexed as

cellular immunityCOVID-19efficacyhumoral immunityimmunitySARS-CoV-2vaccines

Identifiers

PMID35335046
PMCPMC8953736
OpenAlexW4220667636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.