ReviewVaccines2022
The Effectiveness of Interventions for Increasing COVID-19 Vaccine Uptake: A Systematic Review.
Review in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 6 syntheses or guidelines pooled it, 114 citations in OpenAlex.
- Media Exposure and Its Association With Vaccine Attitudes, Intentions, and Hesitancy: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Interventions Addressing Vaccine Hesitancy in the WHO European Region and in North America (United States and Canada): A Systematic Review.Public health reviews · 2026Pooled it
- Effectiveness and cost-effectiveness of interventions to increase knowledge and awareness of attention deficit hyperactivity disorder: a systematic review.European child & adolescent psychiatry · 2025Pooled it
- Communication-based interventions to increase COVID-19 vaccine willingness and uptake: a systematic review with meta-analysis.BMJ open · 2025Pooled it
- Interventions for COVID-19 Vaccine Hesitancy: A Systematic Review and Narrative Synthesis.International journal of environmental research and public health · 2023Pooled it
- COVID-19 vaccine acceptance and hesitancy among patients with cancer: a systematic review and meta-analysis.Public health · 2022Pooled it
- Web-Based Video Intervention and Associated Factors for the Uptake of the Catch-Up Human Papillomavirus Vaccination in Japan: Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- Tough talks COVID-19 (TT-C) digital health intervention: multistate randomized controlled trial.Scientific reports · 2025Trial
- Practice Facilitation to Support Primary Care Physicians With COVID-19 Vaccine Uptake: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Behaviorally Informed Text Message Nudges to Schedule COVID-19 Vaccinations: A Randomized Controlled Trial.Journal of general internal medicine · 2025Trial
- An effective COVID-19 vaccine hesitancy intervention focused on the relative risks of vaccination and infection.Scientific reports · 2024Trial
- "How" Versus "Why" Messaging to Increase Uptake of Booster Vaccination Against COVID-19: Results of a Pragmatic Randomized Trial.Journal of general internal medicine · 2024Trial
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- Loss-framing of information and pre-vaccination consultation improve COVID-19 vaccine acceptance: A survey experiment.Frontiers in public health · 2023Trial
- Dynamic trends and determinants of COVID-19 vaccine hesitancy among adults in China during 2021-2022: A multilevel analysis based on four national cross-sectional surveys.Human vaccines & immunotherapeutics · 2026Article
- Community-led vaccine strategies to boost COVID-19 vaccine uptake among racialized immigrant groups in Parc Extension, Quebec: a strengths-based exemplar study.Canadian journal of public health = Revue canadienne de sante publique · 2026Article
- Personalized feedback about immunity corrects risk misestimation and motivates vaccination.PNAS nexus · 2026Article
- Grocery store workers' knowledge, attitudes, and barriers influencing uptake of COVID-19 vaccine in the United States: a qualitative study.BMC public health · 2026Article
- Impact of Vaccination-Differentiated Public Health and Social Measures on Vaccine Uptake Among the Vaccine Hesitant.AJPM focus · 2026Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vaccination is vital to protect the public against COVID-19. The aim of this systematic review is to identify and evaluate the effectiveness of interventions to increase COVID-19 vaccine uptake. We searched a range of databases (Embase, Medline, Psychology & Behavioral Science, PsycInfo, Web of Science and NIH Preprints Portfolio) from March 2020 to July 2021 for studies which reported primary quantitative or qualitative research on interventions to increase COVID-19 vaccine uptake. Outcome measures included vaccination uptake and reported intention to vaccinate. Reviews, position papers, conference abstracts, protocol papers and papers not in English were excluded. The NHLBI quality assessment was used to assess risk of bias. In total, 39 studies across 33 papers met the inclusion criteria. A total of 28 were assessed as good quality. They included interventions relating to communication content, communication delivery, communication presentation, policy or vaccination delivery, with 7 measuring vaccination uptake and 32 measuring vaccination intention. A narrative synthesis was conducted, which highlighted that there is reasonable evidence from studies investigating real behaviour suggesting that personalising communications and sending booking reminders via text message increases vaccine uptake. Findings on vaccination intention are mixed but suggest that communicating uncertainty about the vaccine does not decrease intention, whereas making vaccination mandatory could have a negative impact. Although much of the research used experimental designs, very few measured real behavioural outcomes. Understanding which interventions are most effective amongst vaccine-hesitant populations and in the context of booster vaccinations will be important as vaccine roll outs continue across the world.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.