Evidence map›Paper›PMID 35334933›Full record

ArticleNutrients2022

Association between Protein Intake and the Risk of Hypertension among Chinese Men and Women: A Longitudinal Study.

Jingjing He, Siwang Yu, Aiping Fang, Xin Shen, Keji Li

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Article
  6. Gut Microbiome Interactions with Oxidative Stress: Mechanisms and Consequences for Health.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jingjing HeSchool of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
Siwang YuSchool of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
Aiping FangSchool of Public Health, Sun Yat-Sen University, Guangzhou 510275, China.
Xin ShenPeking University Cancer Hospital, Beijing 100142, China.
Keji LiSchool of Public Health, Peking University Health Science Centre, Beijing 100191, China.
Peking University · CNPeking University Cancer Hospital · CNSun Yat-sen University · CN

Funding

MONITORING SOCIAL CHANGE: HEALTH, REPRODUCTION, AGINGR01HD030880 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ADAIR, LINDA S, POPKIN, BARRY M · 1994 to 2024
$27.0M
Monitoring Social Change: Dynamics Of Aging And Cognitive FunctionR01AG065357 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ADAIR, LINDA S, POPKIN, BARRY M · 2020 to 2024
$3.6M
Emergence of Cardiometabolic Risk Across the Lifecycle in ChinaR01HL108427 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GORDON-LARSEN, PENNY · 2012 to 2015
$2.7M
Transition to a Western diet and cardiometabolic risk: biomarkers derived from the microbiomeR01DK104371 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GORDON-LARSEN, PENNY · 2015 to 2018
$2.5M
Nutrition-Related NCD Prevention Training in ChinaD43TW009077 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI POPKIN, BARRY M · 2011 to 2015
$1.1M
FIC NIH HHS D43 TW009077NHLBI NIH HHS R01 HL108427NIA NIH HHS R01 AG065357NICHD NIH HHS R01 HD030880NIDDK NIH HHS R01 DK104371
6 · The paper itself

Abstract

This study aimed to examine the relationship between hypertension risk and protein intake in Chinese individuals. Our analysis included 7007 men and 7752 women from 9 China Health and Nutrition Survey waves (1991−2015). The main outcome was incident hypertension. Dietary intake was recorded using a combination of 3 consecutive 24-h recalls and a household food inventory survey. Energy-adjusted cumulative average intakes were analyzed, and Cox proportional hazards regression models were built. After 143,035 person-years of follow-up, 2586 and 2376 new male and female hypertension cases were identified, respectively. In multivariate-adjusted models with dietary protein intakes included as categorical variables, higher animal protein intake was associated with lower hypertension risk in women (p-trend = 0.01), whereas non-significant in men. Plant protein intake showed a significant positive correlation with hypertension risk, while non-significant for total protein. On a continuous scale, restricted cubic spline curves visually revealed L-, J-, and U-shaped associations between hypertension risk and animal-, plant-, and total-protein intakes, respectively, in both sexes (all p-nonlinearity < 0.0001). Our results suggest a beneficial association between intakes of animal, plant, and total proteins and hypertension risk at lower intake levels, and excessive intake of plant or total protein may increase the hypertension risk in the Chinese population.

Indexed as

HypertensionChinaFemaleHumansLongitudinal StudiesMaleNutrition SurveysRisk Factorsanimal proteinChina Health and Nutrition Surveyhypertensionplant proteintotal protein

Identifiers

PMID35334933
PMCPMC8955461
OpenAlexW4220906817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.