Evidence map›Paper›PMID 35334850›Full record

ArticleNutrients2022

Insights into the Composition of a Co-Culture of 10 Probiotic Strains (OMNi BiOTiC

Bernhard Kienesberger, Beate Obermüller, Georg Singer, Christoph Arneitz, Paolo Gasparella, Ingeborg Klymiuk, Angela Horvath, Vanessa Stadlbauer, Christoph Magnes, Elmar Zügner and 6 more

Abstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Gut Microbiome Recovery inDiseases (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Bernhard KienesbergerDepartment of Paediatric and Adolescent Surgery, Medical University of Graz, 8034 Graz, Austria.ORCID 0000-0002-5514-8657
Beate ObermüllerDepartment of Paediatric and Adolescent Surgery, Medical University of Graz, 8034 Graz, Austria.
Georg SingerDepartment of Paediatric and Adolescent Surgery, Medical University of Graz, 8034 Graz, Austria.ORCID 0000-0003-4770-3144
Christoph ArneitzDepartment of Paediatric and Adolescent Surgery, Medical University of Graz, 8034 Graz, Austria.
Paolo GasparellaDepartment of Paediatric and Adolescent Surgery, Medical University of Graz, 8034 Graz, Austria.ORCID 0000-0002-3868-9136
Ingeborg KlymiukDepartment of Cell Biology, Histology and Embryology, Medical University of Graz, 8034 Graz, Austria.ORCID 0000-0001-8755-0037
Angela HorvathDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, 8034 Graz, Austria.ORCID 0000-0001-7279-0628
Vanessa StadlbauerDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, 8034 Graz, Austria.ORCID 0000-0001-5508-8271
Christoph MagnesHealth-Institute for Biomedicine and Health Sciences, Joanneum Research, 8010 Graz, Austria.ORCID 0000-0002-5153-7444
Elmar ZügnerHealth-Institute for Biomedicine and Health Sciences, Joanneum Research, 8010 Graz, Austria.ORCID 0000-0001-7124-2793
Pablo López-GarcíaCenter of Biomarker Research (CBmed), 8034 Graz, Austria.
Slave TrajanoskiCore Facility Computational Bioanalytics, Medical University of Graz, 8034 Graz, Austria.ORCID 0000-0001-6667-8955
Wolfram MiekischDepartment of Anesthesiology and Intensive Care, Rostock University Medical Center, 18057 Rostock, Germany.ORCID 0000-0003-1619-0315
Patricia FuchsDepartment of Anesthesiology and Intensive Care, Rostock University Medical Center, 18057 Rostock, Germany.ORCID 0000-0002-0055-6098
Holger TillDepartment of Paediatric and Adolescent Surgery, Medical University of Graz, 8034 Graz, Austria.
Christoph CastellaniDepartment of Paediatric and Adolescent Surgery, Medical University of Graz, 8034 Graz, Austria.ORCID 0000-0002-4512-3640

Funding

Austrian Research Promoting Agency 867991Institut Allergosan, Graz, Austria n/a
6 · The paper itself

Abstract

backgroundWe aimed to gain insights in a co-culture of 10 bacteria and their postbiotic supernatant.

methodsAbundances and gene expression were monitored by shotgun analysis. The supernatant was characterized by liquid chromatography mass spectroscopy (LC-MS) and gas chromatography mass spectroscopy (GC-MS). Supernatant was harvested after 48 h (S48) and 196 h (S196). Susceptibility testing included nine bacteria and

resultsA time-dependent decrease of the relative abundances and gene expression of

conclusionsThe postbiotic supernatant had positive antibacterial and antifungal effects in vitro and promoted the growth of distinct bacteria in vivo.

Indexed as

ProbioticsAnimalsAnti-Bacterial AgentsBacteriaCandida albicansCoculture TechniquesMiceAnti-Bacterial Agentsculturemicrobiomepostbioticshotgun keywordsusceptibilityvolatile organic compound

Identifiers

PMID35334850
PMCPMC8952306

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.