Evidence map›Paper›PMID 35334832›Full record

ArticleNutrients2022

Nutrition, Overweight, and Cognition in Euthymic Bipolar Individuals Compared to Healthy Controls.

Bernd Reininghaus, Nina Dalkner, Christiane Schörkhuber, Eva Fleischmann, Frederike T Fellendorf, Michaela Ratzenhofer, Alexander Maget, Martina Platzer, Susanne A Bengesser, Adelina Tmava-Berisha and 4 more

Abstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bernd ReininghausDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Nina DalknerDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.ORCID 0000-0001-7716-3674
Christiane SchörkhuberDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Eva FleischmannDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Frederike T FellendorfDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.ORCID 0000-0001-7215-3848
Michaela RatzenhoferDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Alexander MagetDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Martina PlatzerDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Susanne A BengesserDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Adelina Tmava-BerishaDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Melanie LengerDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Robert QueissnerDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.
Elena M D SchönthalerDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.ORCID 0000-0002-9645-4503
Eva Z ReininghausDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, 8036 Graz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bipolar disorder (BD) is associated with impairments in cognitive functions, in which metabolic factors, e.g., overweight, seem to play a significant role. The aim of this study was to investigate the association between nutritional factors and cognitive performance in euthymic individuals with BD. A study cohort of 56 euthymic individuals with BD was compared to a sample of 53 mentally healthy controls. To assess cognitive function, the following tests were applied: California Verbal Learning Test, Trail Making Test A/B, d2 Test of Attention-Revised, and Stroop's Color-Word Interference Test. Furthermore, a 4-day food record was processed to evaluate dietary intake of macronutrients, specific micronutrients, and food diversity. Body mass index and waist to height ratio were calculated to assess overweight and central obesity. Results showed no nutritional differences between individuals with BD and controls. Individuals with BD performed worse in the d2 test than controls. Hierarchical regression analyses yielded no association between cognitive and nutritional parameters. However, waist to height ratio was negatively correlated with almost all cognitive tests. Central obesity seems to affect cognitive functioning in BD, while the lack of finding differences in nutritional data might be due to problems when collecting data and the small sample size. Consequently, further studies focusing on objectively measuring food intake with adequate sample size are needed.

Indexed as

Bipolar DisorderOverweightAttentionCognitionHumansNeuropsychological Testsbipolar disordercognitive functionnutritionoverweight

Identifiers

PMID35334832
PMCPMC8955549

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.