Evidence map›Paper›PMID 35334653›Full record

ArticleMicromachines2022

Viscoelastic Particle Focusing and Separation in a Spiral Channel.

Haidong Feng, Alexander R Jafek, Bonan Wang, Hayden Brady, Jules J Magda, Bruce K Gale

Abstract read
In one paragraph

Article in Micromachines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Exploitation of elasto-inertial fluid flow for the separation of nano-sized particles: Simulating the isolation of extracellular vesicles.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2023
    Article
  6. Deciphering viscoelastic cell manipulation in rectangular microchannels.Physics of fluids (Woodbury, N.Y. : 1994) · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haidong FengDepartment of Mechanical Engineering, University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0003-1350-4841
Alexander R JafekDepartment of Mechanical Engineering, University of Utah, Salt Lake City, UT 84112, USA.
Bonan WangDepartment of Chemical Engineering, University of Utah, Salt Lake City, UT 84112, USA.
Hayden BradyDepartment of Mechanical Engineering, University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0002-8668-8242
Jules J MagdaDepartment of Chemical Engineering, University of Utah, Salt Lake City, UT 84112, USA.
Bruce K GaleDepartment of Mechanical Engineering, University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0001-5843-3464

Funding

Sperm sample preparation for point of care applicationsR44HD095355 · NICHD · NANONC, INC. · PI ASTON, KENNETH IVAN, GALE, BRUCE · 2018 to 2020
$1.2M
NICHD NIH HHS R44 HD095355NIH HHS 5R44HD095355-03Office of Science DE-SC0019285
6 · The paper itself

Abstract

As one type of non-Newtonian fluid, viscoelastic fluids exhibit unique properties that contribute to particle lateral migration in confined microfluidic channels, leading to opportunities for particle manipulation and separation. In this paper, particle focusing in viscoelastic flow is studied in a wide range of polyethylene glycol (PEO) concentrations in aqueous solutions. Polystyrene beads with diameters from 3 to 20 μm are tested, and the variation of particle focusing position is explained by the coeffects of inertial flow, viscoelastic flow, and Dean flow. We showed that particle focusing position can be predicted by analyzing the force balance in the microchannel, and that particle separation resolution can be improved in viscoelastic flows.

Indexed as

inertial focusingparticle separationspiral channelviscoelastic flow

Identifiers

PMID35334653
PMCPMC8954746

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.