Evidence map›Paper›PMID 35334585›Full record

ArticleMedicina (Kaunas, Lithuania)2022

Mitigating Benzodiazepine Dependence and the Risk of Drug-Induced QTc Prolongation in the Treatment of Gastroparesis: A Case Report.

Karley Tranchina, Derek Matlock, Carlos Hernandez, Jacques Turgeon, Jennifer M Bingham

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Karley TranchinaCollege of Pharmacy, University of Arizona, Tucson, AZ 85721, USA.
Derek MatlockMedWiseRx, 100 N Stone Ave., Tucson, AZ 85701, USA.
Carlos HernandezMedWiseRx, 100 N Stone Ave., Tucson, AZ 85701, USA.
Jacques TurgeonTabula Rasa HealthCare Group, Precision Pharmacotherapy Research and Development Institute, 13485 Veterans Way, Orlando, FL 32827, USA.ORCID 0000-0002-7978-9280
Jennifer M BinghamTabula Rasa HealthCare Group, Office of Translational Research and Residency Programs, 228 Strawbridge Dr, Moorestown, NJ 08057, USA.ORCID 0000-0003-4892-7879
Healthwise · USResearch & Development Institute · USUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients are often faced with challenges when it comes to safe therapeutic options. An 89-year-old female with a history of arrhythmias and refractory gastroparesis complained of adverse drug events from her benzodiazepine. While performing a comprehensive medication review and a medication safety review using an advanced clinical decision support system, the pharmacist successfully tapered off the benzodiazepine to a safer alternative antidepressant indicated for the treatment of gastroparesis. Special attention was given to selecting drugs with less QT prolongation risk, based on her age, current drug regimen, previous medical history, and presence of polypharmacy.

Indexed as

GastroparesisLong QT SyndromeAged, 80 and overArrhythmias, CardiacBenzodiazepinesElectrocardiographyFemaleHumansBenzodiazepinesbenzodiazepine dependencegastroparesismedication safetypharmacistQTc prolongation

Identifiers

PMID35334585
PMCPMC8951483
OpenAlexW4220950601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.