Evidence map›Paper›PMID 35334091›Full record

ReviewTissue engineering and regenerative medicine2022

Nanomaterial for Skeletal Muscle Regeneration.

Gun-Jae Jeong, Hannah Castels, Innie Kang, Berna Aliya, Young C Jang

Open access · bronzeAbstract readReview
In one paragraph

Review in Tissue engineering and regenerative medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  16. Immunomodulation for Tissue Repair and Regeneration.Tissue engineering and regenerative medicine · 2023
    Review
  17. Functional hydrogels for the repair and regeneration of tissue defects.Frontiers in bioengineering and biotechnology · 2023
    Review
  18. Article
  19. Nano-sized Materials for Tissue Regeneration and Immune/Cancer Therapy.Tissue engineering and regenerative medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gun-Jae JeongDepartment of Orthopedics, Emory Musculoskeletal Institute, Emory School of Medicine, Atlanta, GA, 30329, USA.
Hannah CastelsDepartment of Orthopedics, Emory Musculoskeletal Institute, Emory School of Medicine, Atlanta, GA, 30329, USA.
Innie KangDepartment of Orthopedics, Emory Musculoskeletal Institute, Emory School of Medicine, Atlanta, GA, 30329, USA.
Berna AliyaDepartment of Orthopedics, Emory Musculoskeletal Institute, Emory School of Medicine, Atlanta, GA, 30329, USA.
Young C JangDepartment of Orthopedics, Emory Musculoskeletal Institute, Emory School of Medicine, Atlanta, GA, 30329, USA. young.jang@emory.edu.ORCID 0000-0002-9489-2104
Georgia Institute of Technology · US

Funding

Engineered Heterochronic Parabiosis on 3D Microphysiological SystemsR01AG072309 · NIA · GEORGIA INSTITUTE OF TECHNOLOGY · PI JANG, YOUNG CHARLES · 2021 to 2025
$1.9M
Implantable biofunctional hydrogel for muscle stem cell transplantationR21AR072287 · NIAMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI JANG, YOUNG CHARLES · 2017 to 2018
$377k
Replicating heterochronic parabiosis on a chip for testing anti-geronic factorsR03AG062976 · NIA · GEORGIA INSTITUTE OF TECHNOLOGY · PI JANG, YOUNG CHARLES · 2019 to 2020
$316k
NIAMS NIH HHS R21 AR072287NIA NIH HHS R01 AG072309NIA NIH HHS R03 AG062976NIH HHS R01AG072309NIH HHS R03AG062976NIH HHS R21AR072287
6 · The paper itself

Abstract

Skeletal muscle has an innate regenerative capacity to restore their structure and function following acute damages and injuries. However, in congenital muscular dystrophies, large volumetric muscle loss, cachexia, or aging, the declined regenerative capacity of skeletal muscle results in muscle wasting and functional impairment. Recent studies indicate that muscle mass and function are closely correlated with morbidity and mortality due to the large volume and location of skeletal muscle. However, the options for treating neuromuscular disorders are limited. Biomedical engineering strategies such as nanotechnologies have been implemented to address this issue.In this review, we focus on recent studies leveraging nano-sized materials for regeneration of skeletal muscle. We look at skeletal muscle pathologies and describe various proof-of-concept and pre-clinical studies that have used nanomaterials, with a focus on how nano-sized materials can be used for skeletal muscle regeneration depending on material dimensionality.Depending on the dimensionality of nano-sized materials, their application have been changed because of their different physical and biochemical properties.Nanomaterials have been spotlighted as a great candidate for addressing the unmet needs of regenerative medicine. Nanomaterials could be applied to several types of tissues and diseases along with the unique characteristics of nanomaterials. However, when confined to muscle tissue, the targets of nanomaterial applications are limited and can be extended in future research.

Indexed as

NanostructuresRegenerationMuscle, SkeletalRegenerative MedicineWound HealingExosomeMuscle regenerationMuscular dystrophyNanomaterialNanoparticle

Identifiers

PMID35334091
PMCPMC8971233
OpenAlexW4220940238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.