ArticleInternational urology and nephrology2022
Factors affecting health-related quality of life in older patients with chronic kidney disease: a single-center cross-sectional study.
Article in International urology and nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Effects of home-based exercise on physical function and health-related quality of life in older patients with pre-dialysis chronic kidney disease: a single-center randomized controlled trial.Clinical and experimental nephrology · 2026Trial
- Deprivation and limitations in daily life in new onset kidney disease: a population study.Clinical kidney journal · 2026Article
- Associations of Objective and Subjective Physical Function With Quality of Life and Well-Being: A Cross-Sectional Study From Ardakan Cohort Study on Aging (ACSA).Health science reports · 2025Article
- Factors associated with improved health-related quality of life due to improvements in physical function and dialysis-related symptoms following intradialytic exercise in outpatients undergoing haemodialysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Potentially modifiable factors associated with health-related quality of life among people with chronic kidney disease: baseline findings from the National Unified Renal Translational Research Enterprise CKD (NURTuRE-CKD) cohort.Clinical kidney journal · 2024Article
- The impact of chronic kidney disease on health-related quality of life (HRQoL): key insights from a hospital-based cross-sectional study.Jornal brasileiro de nefrologiaArticle
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Authors and funding
8 authors.
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Abstract
backgroundHealth-related quality of life (HRQoL) assessment is important for patients with chronic kidney disease (CKD). However, few studies have examined factors related to HRQoL, such as physical function, in older patients with predialysis CKD. This study evaluated the relationship between physical function, renal function, and nutritional status on the HRQoL in this patient group.
methodsThis cross-sectional study included 61 patients aged ≥ 65 years with stages 3-5 predialysis CKD who were admitted for CKD education purposes. Using the EuroQoL 5-dimension 5-level (EQ-5D-5L) health status measure, the percentages of each EQ-5D-5L item were investigated. Physical function was measured using the short physical performance battery (SPPB) and grip strength, and characteristics, such as age, sex, diabetes mellitus, estimated glomerular filtration rate, and Geriatric Nutrition Risk Index, were investigated. Factors associated with EQ-5D-5L were identified using multiple regression analysis.
resultsMore than half of respondents (34/61, 55.7%) selected the second or higher level "have a problem" for the pain/discomfort section. The EQ-5D-5L score was significantly correlated with grip strength (r = 0.34, p = 0.01) and SPPB (r = 0.59, p = 0.00) in a single correlation analysis. Only SPPB (β = 0.67, p = 0.00) remained a significant factor after adjustment for grip strength, SPPB, age, sex, diabetes mellitus, and estimated glomerular filtration rate.
conclusionPhysical function may be an important factor influencing HRQoL in older patients with predialysis CKD.
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