Evidence map›Paper›PMID 35334031›Full record

ArticleJournal of community health2022

A SARS-CoV-2 Outbreak Among Nursing Home Residents Vaccinated with a Booster Dose of mRNA COVID-19 Vaccine.

Giancarlo Ripabelli, Michela Lucia Sammarco, Giovanni Rezza, Antonio D'Amico, Roberta De Dona, Mariagrazia Iafigliola, Albino Parente, Nicandro Samprati, Arturo Santagata, Carmen Adesso and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of community health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
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  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Giancarlo RipabelliDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy. ripab@unimol.it.ORCID 0000-0002-9953-7769
Michela Lucia SammarcoDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy.
Giovanni RezzaHead Prevention Directorate, Ministry of Health, Rome, Italy.
Antonio D'AmicoSchool of Specialization in Hygiene and Preventive Medicine, University of Molise, Campobasso, Italy.
Roberta De DonaSchool of Specialization in Hygiene and Preventive Medicine, University of Molise, Campobasso, Italy.
Mariagrazia IafigliolaSchool of Specialization in Hygiene and Preventive Medicine, University of Molise, Campobasso, Italy.
Albino ParenteSchool of Specialization in Hygiene and Preventive Medicine, University of Molise, Campobasso, Italy.
Nicandro SampratiSchool of Specialization in Hygiene and Preventive Medicine, University of Molise, Campobasso, Italy.
Arturo SantagataSchool of Specialization in Hygiene and Preventive Medicine, University of Molise, Campobasso, Italy.
Carmen AdessoSchool of Specialization in Hygiene and Preventive Medicine, University of Molise, Campobasso, Italy.
Anna NataleSchool of Specialization in Hygiene and Preventive Medicine, University of Molise, Campobasso, Italy.
Michela Anna Di PalmaSchool of Specialization in Hygiene and Preventive Medicine, University of Molise, Campobasso, Italy.
Fabio CannizzaroSchool of Specialization in Hygiene and Preventive Medicine, University of Molise, Campobasso, Italy.
Cosimo Dentizzi"Don Carlo Pistilli" Nursing Home, Campobasso, Italy.
Paola StefanelliDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Manuela TamburroDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy.
University of Molise · ITIstituto Superiore di Sanità · ITMinistero della Salute · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study describes a SARS-CoV-2 outbreak caused by the Delta (B.1.617.2) variant in a nursing home in Central Italy during October-November 2021. Trained interviewers collected data from residents, staff, and administration officers with an agreed informed consent procedure. Thirty-two (44.5%) out of 72 residents (median age 89 years) and six (26.1%) of 23 healthcare workers were found to be infected with SARS-CoV-2. Infections occurred more often among residents with a higher index of independence in daily living activities, suggesting an increased risk for those with more interactions. Twenty-five infected residents (78.1%) received the booster dose of mRNA anti-COVID-19 vaccine > 7 days before SARS-CoV-2 onset. Half of the infected residents had mild symptoms, and only three required hospitalisation, one of whom died from COVID-19 complications. The study underlines the effectiveness of a booster dose in providing a high protection against severe disease and hospitalisation even among vulnerable individuals infected with the Delta variant of concern.

Indexed as

COVID-19COVID-19 VaccinesAged, 80 and overDisease OutbreaksHumansNursing HomesRNA, MessengerSARS-CoV-2COVID-19 VaccinesRNA, MessengerCOVID-19ElderlyImpact of vaccinationMild diseaseThird dose

Identifiers

PMID35334031
PMCPMC8949830
OpenAlexW4221130777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.