ArticleThe British journal of radiology2022
Muscle fat infiltration but not muscle cross-sectional area is independently associated with bone mineral density at the lumbar spine.
Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Fatty infiltration and cross-sectional area as indicators of muscle mass in osteoporosis: a meta-regression study.Frontiers in endocrinology · 2025Pooled it
- Effect of exercise modality and weight loss on changes in muscle and bone quality in older adults with obesity.Experimental gerontology · 2023Trial
- Construction of musculoskeletal quantitative model based on deep learning and study of musculoskeletal relationship in patients with osteoporosis.Journal of advanced research · 2026Article
- Comparative clinical utility of preoperative psoas muscle and skeletal muscle index cutoffs for risk stratification after esophagectomy.Surgery today · 2026Article
- Association between myosteatosis and bone mineral density in postmenopausal women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Diagnostic Perspectives on the Relationship Between Paraspinal Muscles and Bone Mineral Density: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- "Muscle quality": rethinking an imprecise term.European geriatric medicine · 2026Review
- Comparison of paravertebral muscle thickness and fatty infiltration in patients with osteoporosis, osteopenia and normal bone mineral density: a single-blind retrospective controlled trial.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Comparative analysis of the correlation between paraspinal muscles fat infiltration and vertebral bone quality in patients with lumbar degenerative diseases.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Impact of high body fat and low muscle mass on bone mineral density in postmenopausal women with type 2 diabetes: A DXA-based cross-sectional study.Aging clinical and experimental research · 2025Article
- Age- and sex-specific relationships between bone mineral density, abdominal fat, and paravertebral muscle.Scientific reports · 2025Article
- Associations between abdominal fat, psoas muscle fat, and lumbar spine bone density: insights from quantitative CT imaging.BMC musculoskeletal disorders · 2025Article
- Association between systemic immune-inflammation index and trimethylamine N-oxide levels in peripheral blood and osteoporosis in overweight and obese patients.Frontiers in endocrinology · 2025Article
- Muscle fat infiltration: a narrative review of the magnetic resonance (MR)-based evaluation methods and their clinical applications.Quantitative imaging in medicine and surgery · 2024Review
- Reduced Cervical Muscle Fat Infiltrate Is Associated with Self-Reported Recovery from Chronic Idiopathic Neck Pain Over Six Months: A Magnetic Resonance Imaging Longitudinal Cohort Study.Journal of clinical medicine · 2024Article
- [Radiographic parameters and influencing factors of paraspinal muscle degeneration in healthy people].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024Article
- Vertebral bone quality score was associated with paraspinal muscles fat infiltration, but not modic classification in patients with chronic low back pain: a prospective cross-sectional study.BMC musculoskeletal disorders · 2024Article
- Exploring the interplay between paraspinal muscular status and bone health in osteoporosis and fracture risk: a comprehensive literature review on computed tomography (CT) and magnetic resonance imaging (MRI) studies.Quantitative imaging in medicine and surgery · 2024Review
- Relation of bone mineral density with fat infiltration of paraspinal muscles: The Goutallier classification.Osteoporosis and sarcopenia · 2024Article
- Relationship between paraspinal muscle properties and bone mineral density based on QCT in patients with lumbar disc herniation.BMC musculoskeletal disorders · 2024Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAlthough sarcopenia and osteoporosis are inter-related conditions that are common with advancing age, few studies have explored relationships between muscle quality and bone mineral density (BMD). We investigated age- and sex-specific paraspinal muscle fat infiltration (MFI), muscle cross-sectional area (CSA), and spine volumetric BMD (vBMD) in healthy Chinese adults.
methods605 healthy adults aged 20-59 years (340 women, mean age 39.2 years; 265 men, mean age 38.8 years) had axial
resultsFemales had lower CSA and higher MFI than males in both the psoas and MF-ES muscles (
conclusionWe have demonstrated that, independent of CSA and demographic variables, MFI of the MF-ES muscles is predictive of lower lumbar spine vBMD in both sexes. ADVANCES IN KNOWLEDGE: This is the first study to demonstrate that, independent of muscle size and demographic variables, MFI of the paraspinal MF-ES muscles is predictive of lower lumbar spine vBMD in both sexes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.