Evidence map›Paper›PMID 35333566›Full record

ArticleScience advances2022

PRP4KA phosphorylates SERRATE for degradation via 20

Lin Wang, Xingxing Yan, Yanjun Li, Zhiye Wang, Shweta Chhajed, Baoshuan Shang, Zhen Wang, Suk Won Choi, Hongwei Zhao, Sixue Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Plant microRNA maturation and function.Nature reviews. Molecular cell biology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Functions and mechanisms of RNA helicases in plants.Journal of experimental botany · 2023
    Review
  18. Intrinsically disordered proteins SAID1/2 condensate on SERRATE for dual inhibition of miRNA biogenesis in Arabidopsis.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  19. microRNA production inFrontiers in plant science · 2023
    Review
  20. Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Lin WangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0001-7787-904X
Xingxing YanDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0002-0140-4029
Yanjun LiDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0003-3822-6470
Zhiye WangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0001-6532-4442
Shweta ChhajedDepartment of Biology, Plant Molecular and Cellular Biology Program, Genetics Institute, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0003-4234-1113
Baoshuan ShangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0002-8744-3554
Zhen WangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.
Suk Won ChoiDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0001-9372-1947
Hongwei ZhaoLaboratory of Bio-interactions and Crop Health, Department of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0001-9107-765X
Sixue ChenDepartment of Biology, Plant Molecular and Cellular Biology Program, Genetics Institute, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-6690-7612
Xiuren ZhangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0001-8982-2999
Texas A&M University · USNanjing Agricultural University · CNState Key Laboratory of Plant Physiology and BiochemistryUniversity of Florida · USNingbo University · CN

Funding

Roles of SWI/SNF complexes in posttranscriptional processing of RNAR01GM132401 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI ZHANG, XIUREN · 2019 to 2022
$1.4M
NIGMS NIH HHS R01 GM132401
6 · The paper itself

Abstract

Phosphorylation can quickly switch on/off protein functions. Here, we reported pre-mRNA processing 4 kinase A (PRP4KA), and its paralogs interact with Serrate (SE), a key factor in RNA processing. PRP4KA phosphorylates at least five residues of SE in vitro and in vivo. Hypophosphorylated, but not hyperphosphorylated, SE variants could readily rescue

Identifiers

PMID35333566
PMCPMC8956257
OpenAlexW4220902066

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.