ArticlePlant physiology2022
OsNAC016 regulates plant architecture and drought tolerance by interacting with the kinases GSK2 and SAPK8.
Article in Plant physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 82 citations in OpenAlex.
- The OsCPK4-OsCNGC7 phosphorylation-centered feedback loop promotes CaPlant communications · 2026Article
- Pan-Genome Analysis Reveals Evolutionary Dynamics and Functional Divergence of thePlants (Basel, Switzerland) · 2026Article
- Crops exposed to extreme conditions: perspectives of gene editing to improve stress tolerance.Plant cell reports · 2026Review
- Genome-Wide Identification, Characterization, Expression Analysis, and Interacting Protein Prediction of thePlants (Basel, Switzerland) · 2026Article
- Genome-wide identification and expression analysis of the SHAGGY-like kinase gene family in foxtail millet (Frontiers in plant science · 2026Article
- Harnessing brassinosteroid signaling in rice: from molecular pathways to environmentally adaptive breeding.Frontiers in plant science · 2026Review
- The GmPRL1b-GmST2-GmAOC3/4 Module Confers Salt Tolerance and Botrytis cinerea Resistance by Inducing Jasmonic Acid Biosynthesis in Soybean.Plant biotechnology journal · 2025Article
- Enhancing drought resilience in crops: mechanistic approaches in the face of climate challenge.Plant molecular biology · 2025Review
- A mini-review on the role of leucine-rich repeat receptor-like kinases (LRR-RLKs) in plant responses to drought stress.Molecular biology reports · 2025Review
- Progress in Transcriptomics and Metabolomics in Plant Responses to Abiotic Stresses.Current issues in molecular biology · 2025Review
- Overexpression of MtNAC33 enhances biomass yield and drought tolerance in alfalfa.Plant biotechnology journal · 2025Article
- Identification ofPlants (Basel, Switzerland) · 2024Article
- The E3 ligase OsPUB33 controls rice grain size and weight by regulating the OsNAC120-BG1 module.The Plant cell · 2024Article
- Review
- Natural variation in the promoter of qRBG1/OsBZR5 underlies enhanced rice yield.Nature communications · 2024Article
- An AP2/ERF transcription factor confers chilling tolerance in rice.Science advances · 2024Article
- Characterization of theInternational journal of molecular sciences · 2024Article
- Histone deacetylase OsHDA716 represses rice chilling tolerance by deacetylating OsbZIP46 to reduce its transactivation function and protein stability.The Plant cell · 2024Article
- Pumpkin CmoDREB2A enhances salt tolerance of grafted cucumber through interaction with CmoNAC1 to regulate HHorticulture research · 2024Article
- OsNAC120 balances plant growth and drought tolerance by integrating GA and ABA signaling in rice.Plant communications · 2024Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ideal plant architecture and drought tolerance are important determinants of yield potential in rice (Oryza sativa). Here, we found that OsNAC016, a rice NAC (NAM, ATAF, and CUC) transcription factor, functions as a regulator in the crosslink between brassinosteroid (BR)-mediated plant architecture and abscisic acid (ABA)-regulated drought responses. The loss-of-function mutant osnac016 exhibited erect leaves and shortened internodes, but OsNAC016-overexpressing plants had opposite phenotypes. Further investigation revealed that OsNAC016 regulated the expression of the BR biosynthesis gene D2 by binding to its promoter. Moreover, OsNAC016 interacted with and was phosphorylated by GSK3/SHAGGY-LIKE KINASE2 (GSK2), a negative regulator in the BR pathway. Meanwhile, the mutant osnac016 had improved drought stress tolerance, supported by a decreased water loss rate and enhanced stomatal closure in response to exogenous ABA, but OsNAC016-overexpressing plants showed attenuated drought tolerance and reduced ABA sensitivity. Further, OSMOTIC STRESS/ABA-ACTIVATED PROTEIN KINASE8 (SAPK8) phosphorylated OsNAC016 and reduced its stability. The ubiquitin/26S proteasome system is an important degradation pathway of OsNAC016 via the interaction with PLANT U-BOX PROTEIN43 (OsPUB43) that mediates the ubiquitination of OsNAC016. Notably, RNA-sequencing analysis revealed global roles of OsNAC016 in promoting BR-mediated gene expression and repressing ABA-dependent drought-responsive gene expression, which was confirmed by chromatin immunoprecipitation quantitative PCR analysis. Our findings establish that OsNAC016 is positively involved in BR-regulated rice architecture, negatively modulates ABA-mediated drought tolerance, and is regulated by GSK2, SAPK8, and OsPUB43 through posttranslational modification. Our data provide insights into how plants balance growth and survival by coordinately regulating the growth-promoting signaling pathway and response under abiotic stresses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.