Evidence map›Paper›PMID 35333293›Full record

ArticleAmerican journal of epidemiology2022

The US Midlife Mortality Crisis Continues: Excess Cause-Specific Mortality During 2020.

Dana A Glei

Abstract read
In one paragraph

Article in American journal of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Evolution of the US nonmetropolitan mortality disadvantage by sex, state, and year, 1999-2019.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Life expectancy changes since COVID-19.Nature human behaviour · 2022
    Article
  11. Article
  12. The impact of the SARS-CoV-2 pandemic on cause-specific mortality patterns: a systematic literature review.Zeitschrift fur Gesundheitswissenschaften = Journal of public health · 2022
    Review
  13. In the Midst of a Pandemic, Introverts May Have a Mortality Advantage.medRxiv : the preprint server for health sciences · 2022
    Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Dana A Glei

Funding

Program Development (Pilot)P30AG012839 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI William H Dow · 1999 to 2026
$18.6M
Monitoring Inter-County Variations in Mortality in the United StatesR03AG058110 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI BARBIERI, MAGALI · 2018 to 2019
$147k
NIA NIH HHS P30 AG012839NIA NIH HHS R03 AG058110
6 · The paper itself

Abstract

Whether monthly excess mortality in the United States during 2020 varied by age and cause of death is investigated in this analysis. Based on national-level death counts and population estimates for 1999-2020, sex-specific negative binomial regression models were used to estimate monthly cause-specific excess mortality by age group during 2020. Among men, 71% non-COVID excess deaths occurred at working ages (25-64 years), but those ages accounted for only 36% of non-COVID excess deaths among women. Many excess deaths resulted from external causes (particularly among men), heart disease, diabetes, Alzheimer disease (particularly among women), and cerebrovascular disease. For men, the largest share of non-COVID excess deaths resulted from external causes, nearly 80% of which occurred at working ages. Although incorrectly classified COVID-19 deaths may explain some excess non-COVID mortality, misclassification is unlikely to explain the increase in external causes of death. Auxiliary analyses suggested that drug-related deaths may be driving the increase in external mortality, but drug overdoses were already increasing for a full year before the pandemic. The oldest Americans bore the brunt of COVID-19 deaths, but working-age Americans, particularly men, suffered substantial numbers of excess non-COVID deaths, most commonly from external causes and heart disease.

Indexed as

COVID-19Heart DiseasesAdultCause of DeathFemaleHumansMaleMiddle AgedModels, StatisticalMortalityPandemicsUnited Statesage variationcause of deathCOVID-19excess mortalityUnited States

Identifiers

PMID35333293
PMCPMC9767865

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.