ArticleMultiple sclerosis (Houndmills, Basingstoke, England)2022
Emergency medical care for multiple sclerosis: A five-year population study in the Campania Region (South Italy).
Article in Multiple sclerosis (Houndmills, Basingstoke, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Subcutaneous Ocrelizumab for the Treatment of Relapsing Forms of Multiple Sclerosis: A Budget Impact Model.PharmacoEconomics - open · 2026Article
- Aging with multiple sclerosis and associated prevalence, incidence, comorbidities and healthcare utilization patterns in a population based study.Scientific reports · 2026Article
- Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis.Annals of clinical and translational neurology · 2026Review
- Neural networks to estimate multiple sclerosis disability and predict progression using routinely collected healthcare data.Multiple sclerosis (Houndmills, Basingstoke, England) · 2025Article
- Multiple Sclerosis in the Emergency Department: A Retrospective Case-Control Study in a Large US Center.Neurology(R) neuroimmunology & neuroinflammation · 2025Article
- Advancing multiple sclerosis management in older adults.Nature reviews. Neurology · 2025Article
- Embodiment of structural racism and multiple sclerosis risk and outcomes in the USA.Nature reviews. Neurology · 2025Review
- Trajectories and management of vascular risk following the diagnosis of multiple sclerosis: A population-based matched cohort study between 1987 and 2018 in England.Multiple sclerosis (Houndmills, Basingstoke, England) · 2024Article
- The Prevalence of Comorbidities and Their Association With Disability Progression in Individuals With Multiple Sclerosis: A Study From Brazil.International journal of MS care · 2024Article
- Utilization of Ocrelizumab within Different Treatment Strategies for Multiple Sclerosis: A 5-Year Population-Based Study.Neurology international · 2024Article
- Impact of COVID-19 and system recovery in delivering healthcare to people with multiple sclerosis: a population-based Study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Etiology, effects and management of comorbidities in multiple sclerosis: recent advances.Frontiers in immunology · 2023Review
- Burden and trends of multiple sclerosis in China from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019.BMJ open · 2022Observational
- Persistence, adherence, healthcare resource utilization and costs for ocrelizumab in the real-world of the Campania Region of Italy.Journal of neurology · 2022Article
- Healthcare utilization in multiple sclerosis: Impact of disease modifying therapies and comorbidities.Multiple sclerosis (Houndmills, Basingstoke, England) · 2022Article
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEmergency hospital admissions are common in multiple sclerosis (MS), and can highlight unmet medical needs.
objectivesTo evaluate burden, predictors and outcomes of MS emergency admissions.
methodsThis is a population-based study, conducted in the Campania Region (South Italy) from 2015 to 2019, using hospital discharge records, drug prescriptions and outpatients. The risk of emergency hospital admissions and the likelihood of worse outcomes were evaluated using the Cox regression and multinomial logistic regression models, respectively, in relation to age, sex, disease-modifying treatments (DMTs), comorbidities and adherence.
resultsWe recorded 1225 emergency admissions for 1001 patients (out of 5765 prevalent MS patients), overall costing 4,143,764.67 EUR. The risk of emergency admissions increased with age (hazard ratio (HR) = 1.02; 95% confidence interval (CI) = 1.01, 1.03;
conclusionWith 17% people with MS requiring emergency medical care over 5 years, improved management of DMTs and comorbidities could potentially reduce their medical, social and financial burden.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.