Evidence map›Paper›PMID 35332665›Full record

ReviewPlant biotechnology journal2022

De novo phasing resolves haplotype sequences in complex plant genomes.

Ji-Yoon Guk, Min-Jeong Jang, Jin-Wook Choi, Yeon Mi Lee, Seungill Kim

Open access · goldAbstract readReview
In one paragraph

Review in Plant biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Evolution of Plant Genome Size and Composition.Genomics, proteomics & bioinformatics · 2024
    Review
  9. Article
  10. The genomes of Australian wild limes.Plant molecular biology · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Recent Advances in Assembly of Complex Plant Genomes.Genomics, proteomics & bioinformatics · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ji-Yoon GukDepartment of Environmental Horticulture, University of Seoul, Seoul, Korea.ORCID 0000-0002-3915-3093
Min-Jeong JangDepartment of Environmental Horticulture, University of Seoul, Seoul, Korea.ORCID 0000-0002-0401-2258
Jin-Wook ChoiDepartment of Environmental Horticulture, University of Seoul, Seoul, Korea.ORCID 0000-0002-0464-3834
Yeon Mi LeeDepartment of Environmental Horticulture, University of Seoul, Seoul, Korea.ORCID 0000-0002-2959-4047
Seungill KimDepartment of Environmental Horticulture, University of Seoul, Seoul, Korea.ORCID 0000-0001-6287-8693
University of Seoul · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome phasing is a recently developed assembly method that separates heterozygous eukaryotic genomic regions and builds haplotype-resolved assemblies. Because differences between haplotypes are ignored in most published de novo genomes, assemblies are available as consensus genomes consisting of haplotype mixtures, thus increasing the need for genome phasing. Here, we review the operating principles and characteristics of several freely available and widely used phasing tools (TrioCanu, FALCON-Phase, and ALLHiC). An examination of downstream analyses using haplotype-resolved genome assemblies in plants indicated significant differences among haplotypes regarding chromosomal rearrangements, sequence insertions, and expression of specific alleles that contribute to the acquisition of the biological characteristics of plant species. Finally, we suggest directions to solve addressing limitations of current genome-phasing methods. This review provides insights into the current progress, limitations, and future directions of de novo genome phasing, which will enable researchers to easily access and utilize genome-phasing in studies involving highly heterozygous complex plant genomes.

Indexed as

Genome, PlantGenomicsAllelesHaplotypesPlantsSequence Analysis, DNAallele-specific expressionautopolyploidchromosomal rearrangementde novo phasinghaplotype-resolved assemblyhaplotype-specific sequence insertionplant genome

Identifiers

PMID35332665
PMCPMC9129073
OpenAlexW4221124270

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.