ArticleCurrent topics in behavioral neurosciences2022
Anhedonia in Anxiety Disorders.
Article in Current topics in behavioral neurosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Abnormal resting-state functional connectivity in anhedonia: A systematic review and meta-analysis.Brain imaging and behavior · 2026Pooled it
- Positive Affect Treatment for Depression, Anxiety, and Low Positive Affect: A Randomized Clinical Trial.JAMA network open · 2026Trial
- A parallel-arm, randomized trial of Behavioral Activation Therapy for anhedonia versus mindfulness-based cognitive therapy for adults with anhedonia.Behaviour research and therapy · 2024Trial
- Amplification of positivity for depression and anxiety: Neural prediction of treatment response.Behaviour research and therapy · 2024Trial
- Amplification of Positivity Treatment for Anxiety and Depression: A Randomized Experimental Therapeutics Trial Targeting Social Reward Sensitivity to Enhance Social Connectedness.Biological psychiatry · 2024Trial
- What good are positive emotions for treatment? A replication test of whether trait positive emotionality predicts response to exposure therapy for social anxiety disorder.Behaviour research and therapy · 2023Trial
- The power of positivity: Exploring affective and social processes of change throughout a positive valence treatment for anxiety or depression.Journal of mood and anxiety disorders · 2025Article
- Trait anxiety is associated with reduced reward-related replay at rest.Nature communications · 2025Article
- From anxiety to depression: A longitudinal investigation into the role of anhedonia.Journal of affective disorders · 2025Article
- What do clients think about amplifying positivity? Client change perspectives following a cognitive and behavioural positive activity intervention for anxiety and depression.Counselling and psychotherapy research · 2025Article
- Article
- Cross-species translational paradigms for assessing positive valence system as defined by the RDoC matrix.Journal of neurochemistry · 2025Review
- The Limbic System in Co-Occurring Substance Use and Anxiety Disorders: A Narrative Review Using the RDoC Framework.Brain sciences · 2024Review
- Assessing social anhedonia in a transdiagnostic sample: Insights from a computational psychiatry lens.Journal of mood and anxiety disorders · 2024Article
- Anhedonia influences threat avoidance and relief: A conceptual replication.Journal of mood and anxiety disorders · 2024Article
- Probabilistic Reinforcement Learning and Anhedonia.Current topics in behavioral neurosciences · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Humans, like other animals, are fundamentally motivated to pursue rewarding outcomes and avoid aversive ones. Anxiety disorders are conceptualized, defined, and treated based on heightened sensitivity to perceived aversive outcomes, including imminent threats as well as those that are uncertain yet could occur in the future. Avoidance is the central strategy used to mitigate anticipated aversive outcomes - often at the cost of sacrificing potential rewards and hindering people from obtaining desired outcomes. It is for these reasons that people are often motivated to seek treatment. In this chapter, we consider whether and how anhedonia - the loss of interest in pursuing and/or reduced responsiveness to rewarding outcomes - may serve as a barrier to recovering from clinically impairing anxiety. Increasingly recognized as a prominent symptom in many individuals with elevated anxiety, anhedonia is not explicitly considered within prevailing theoretical models or treatment approaches of anxiety. Our goal, therefore, is to review what is known about anhedonia within the anxiety disorders and then integrate this knowledge into a functional perspective to consider how anhedonia could maintain anxiety and limit treatment response. Our overarching thesis is that anhedonia disrupts the key processes that are central to supporting anxiety recovery. We end this chapter by considering how explicitly targeting anhedonia in treatment can optimize outcomes for anxiety disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.