Evidence map›Paper›PMID 35332404›Full record

ArticleSurgical case reports2022

Conversion surgery following gemcitabine plus cisplatin therapy for initially unresectable gallbladder cancer with peritoneal carcinomatosis: a case report.

Yusuke Wakasa, Yoshikazu Toyoki, Tomomi Kusumi, Yuma Kameyama, Tadashi Odagiri, Hiroyuki Jin, Makoto Nakai, Kazunori Aoki, Hiroaki Kawashima, Masaaki Endo

Open access · goldAbstract read
In one paragraph

Article in Surgical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yusuke WakasaDepartment of General Surgery, Aomori City Hospital, 1-14-20, Katta, Aomori, 030-0821, Japan. wa1022ka@yahoo.co.jp.ORCID http://orcid.org/0000-0001-9106-6002
Yoshikazu ToyokiDepartment of General Surgery, Aomori City Hospital, 1-14-20, Katta, Aomori, 030-0821, Japan.
Tomomi KusumiDepartment of Pathology, Aomori City Hospital, Aomori, Japan.
Yuma KameyamaDepartment of General Surgery, Aomori City Hospital, 1-14-20, Katta, Aomori, 030-0821, Japan.
Tadashi OdagiriDepartment of General Surgery, Aomori City Hospital, 1-14-20, Katta, Aomori, 030-0821, Japan.
Hiroyuki JinDepartment of General Surgery, Aomori City Hospital, 1-14-20, Katta, Aomori, 030-0821, Japan.
Makoto NakaiDepartment of General Surgery, Aomori City Hospital, 1-14-20, Katta, Aomori, 030-0821, Japan.
Kazunori AokiDepartment of General Surgery, Aomori City Hospital, 1-14-20, Katta, Aomori, 030-0821, Japan.
Hiroaki KawashimaDepartment of General Surgery, Aomori City Hospital, 1-14-20, Katta, Aomori, 030-0821, Japan.
Masaaki EndoDepartment of General Surgery, Aomori City Hospital, 1-14-20, Katta, Aomori, 030-0821, Japan.
Aomori Rosai Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConversion surgery, which is defined as chemotherapy or chemoradiotherapy followed by radical surgery, may improve survival of patients with initially unresectable advanced biliary tract cancer, including gallbladder cancer. However, there are few reports on conversion surgery for advanced gallbladder cancer. CASE PRESENTATION: A 69-year-old woman was referred to our hospital with initially unresectable gallbladder cancer with peritoneal carcinomatosis. She underwent gemcitabine plus cisplatin therapy for 9 months. Extended cholecystectomy, resection of the extrahepatic bile duct with regional lymph node dissection, and total omentectomy were then performed as conversion surgery. The patient has survived without recurrence for 19 months postoperatively (31 months after the initial diagnosis) while continuing chemotherapy.

conclusionsThis case suggests that conversion surgery for advanced gallbladder cancer is effective and may be curative for locally advanced disease and distant metastasis such as peritoneal carcinomatosis.

Indexed as

Conversion surgeryGallbladder cancerGemcitabine plus cisplatin therapyInitially unresectablePeritoneal carcinomatosis

Identifiers

PMID35332404
PMCPMC8948309
OpenAlexW4220765374

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.