ArticleCommunications biology2022
Multiscale reconstruction of various vessels in the intact murine liver lobe.
Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 25 citations in OpenAlex.
- Article
- A Novel 3D Visualization Method in Mice Identifies the Periportal Lamellar Complex (PLC) as a Key Regulator of Hepatic Ductal and Neuronal Branching Morphogenesis.bioRxiv : the preprint server for biology · 2026Article
- Liver sinusoid constraints make random search of CD8 T cells for Plasmodium parasites efficient.bioRxiv : the preprint server for biology · 2025Article
- High-Resolution Quantitative Reconstruction of Microvascular Architectures in Mouse Hepatocellular Carcinoma Models.Cancers · 2025Article
- Neuroprotective liver portal area macrophages attenuate hepatic inflammation.Nature immunology · 2025Article
- Generation of a High-Precision Whole Liver Panorama and Cross-Scale 3D Pathological Analysis for Hepatic Fibrosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Precise reconstruction of the entire mouse kidney at cellular resolution.Biomedical optics express · 2024Article
- Cross-scale tracing of nanoparticles and tumors at the single-cell level using the whole-lung atlas.Science advances · 2023Article
- A high-performance deep-learning-based pipeline for whole-brain vasculature segmentation at the capillary resolution.Bioinformatics (Oxford, England) · 2023Article
- Multiscale reconstruction of bronchus and cancer cells in human lung adenocarcinoma.Biomedical engineering online · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The liver contains a variety of vessels and participates in miscellaneous physiological functions. While past studies generally focused on certain hepatic vessels, we simultaneously obtained all the vessels and cytoarchitectural information of the intact mouse liver lobe at single-cell resolution. Here, taking structural discrepancies of various vessels into account, we reconstruct and visualize the portal vein, hepatic vein, hepatic artery, intrahepatic bile duct, intrahepatic lymph of an intact liver lobe and peribiliary plexus in its selected local areas, providing a technology roadmap for studying the fine hepatic vascular structures and their spatial relationship, which will help research into liver diseases and evaluation of medical efficacies in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.