ArticleCommunications biology2022
Brain connectivity fingerprinting and behavioural prediction rest on distinct functional systems of the human connectome.
Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Human brain fingerprint-like nodes within RSFC: an exploratory study and their role in RSFC-behavior associations.Brain imaging and behavior · 2026Article
- Representing Brain-Behavior Associations by Retaining High-Motion Minoritized Youth.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Brain connectivity fingerprinting as a predictive biomarker of art therapy outcomes in Parkinson's disease.Research square · 2026Article
- Divergence unveils further distinct phenotypic traits of human brain connectomics fingerprint.iScience · 2026Article
- Sources of outdoor air pollution exposure and child brain network development across the United States.bioRxiv : the preprint server for biology · 2025Article
- Large-scale comparative analysis reveals top graph signal processing features for subject identification.bioRxiv : the preprint server for biology · 2025Article
- Voxel-Wise or Region-Wise Nuisance Regression for Functional Connectivity Analyses: Does It Matter?Human brain mapping · 2025Article
- Identifying individuals from their brain natural frequency fingerprints.Scientific reports · 2025Article
- Spine-Prints: Transposing Brain Fingerprints to the Spinal Cord.bioRxiv : the preprint server for biology · 2025Article
- Multimodal identification of the mouse brain using simultaneous CaCommunications biology · 2025Article
- Brain functional connectivity and anatomical features as predictors of cognitive behavioral therapy outcome for anxiety in youths.Psychological medicine · 2025Article
- Idiosyncrasy and generalizability of contraceptive- and hormone-related functional connectomes across the menstrual cycle.Network neuroscience (Cambridge, Mass.) · 2025Article
- Connectome-based fingerprinting: reproducibility, precision, and behavioral prediction.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Integrative, segregative, and degenerate harmonics of the structural connectome.Communications biology · 2024Article
- A Demographic-Conditioned Variational Autoencoder for fMRI Distribution Sampling and Removal of Confounds.ArXiv · 2024Article
- Edge time series components of functional connectivity and cognitive function in Alzheimer's disease.Brain imaging and behavior · 2024Article
- Higher general intelligence is associated with stable, efficient, and typical dynamic functional brain connectivity patterns.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- The abilities of movie-watching functional connectivity in individual identifications and individualized predictions.Brain imaging and behavior · 2023Article
- Edge Time Series Components of Functional Connectivity and Cognitive Function in Alzheimer's Disease.medRxiv : the preprint server for health sciences · 2023Article
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4 authors.
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Abstract
The prediction of inter-individual behavioural differences from neuroimaging data is a rapidly evolving field of research focusing on individualised methods to describe human brain organisation on the single-subject level. One method that harnesses such individual signatures is functional connectome fingerprinting, which can reliably identify individuals from large study populations. However, the precise relationship between functional signatures underlying fingerprinting and behavioural prediction remains unclear. Expanding on previous reports, here we systematically investigate the link between discrimination and prediction on different levels of brain network organisation (individual connections, network interactions, topographical organisation, and connection variability). Our analysis revealed a substantial divergence between discriminatory and predictive connectivity signatures on all levels of network organisation. Across different brain parcellations, thresholds, and prediction algorithms, we find discriminatory connections in higher-order multimodal association cortices, while neural correlates of behaviour display more variable distributions. Furthermore, we find the standard deviation of connections between participants to be significantly higher in fingerprinting than in prediction, making inter-individual connection variability a possible separating marker. These results demonstrate that participant identification and behavioural prediction involve highly distinct functional systems of the human connectome. The present study thus calls into question the direct functional relevance of connectome fingerprints.
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