Evidence map›Paper›PMID 35332170›Full record

ArticleScientific reports2022

A portrait of obstructive sleep apnea risk factors in 27,210 middle-aged and older adults in the Canadian Longitudinal Study on Aging.

Cynthia Thompson, Julie Legault, Gregory Moullec, Marc Baltzan, Nathan Cross, Thien Thanh Dang-Vu, Marie-Ève Martineau-Dussault, Patrick Hanly, Najib Ayas, Dominique Lorrain and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The effect of gender on clinical characteristics and diagnostic process of obstructive sleep apnea syndrome.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. A [Journal of neuroinflammation · 2025
    Article
  8. Article
  9. Prevalence and predictors of obstructive sleep apnea in collegiate football players.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Heart failure with preserved ejection fraction risk is associated with prevalence and severity of obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  18. Review
  19. Article
  20. Microglia and Sleep Disorders.Advances in neurobiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cynthia Thompson *Center for Advanced Research in Sleep Medicine, CIUSSS Nord-de-L'Ile-de-Montréal, Montreal, Canada.
Julie Legault *Center for Advanced Research in Sleep Medicine, CIUSSS Nord-de-L'Ile-de-Montréal, Montreal, Canada.
Gregory MoullecCenter for Advanced Research in Sleep Medicine, CIUSSS Nord-de-L'Ile-de-Montréal, Montreal, Canada.
Marc BaltzanMount Sinai Hospital Center, Montreal, Canada.
Nathan CrossInstitut Universitaire de Gériatrie de Montréal and CRIUGM, CIUSSS du Centre-Sud-de-L'Ile-de-Montréal, Montreal, Canada.
Thien Thanh Dang-VuInstitut Universitaire de Gériatrie de Montréal and CRIUGM, CIUSSS du Centre-Sud-de-L'Ile-de-Montréal, Montreal, Canada.
Marie-Ève Martineau-DussaultCenter for Advanced Research in Sleep Medicine, CIUSSS Nord-de-L'Ile-de-Montréal, Montreal, Canada.
Patrick HanlySleep Centre, Foothills Medical Centre, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Najib AyasDepartment of Medicine, University of British Columbia, Vancouver, BC, Canada.
Dominique LorrainResearch Centre On Aging, University Institute of Geriatrics of Sherbrooke, CIUSSS de l'Estrie - CHUS, Sherbrooke, Canada.
Gillian EinsteinDepartment of Psychology, University of Toronto, Toronto, Canada.
Julie CarrierCenter for Advanced Research in Sleep Medicine, CIUSSS Nord-de-L'Ile-de-Montréal, Montreal, Canada.
Nadia GosselinCenter for Advanced Research in Sleep Medicine, CIUSSS Nord-de-L'Ile-de-Montréal, Montreal, Canada. nadia.gosselin@umontreal.ca.

Funding

CIHR FDN154291CIHR LSA 94473
6 · The paper itself

Abstract

Determining the prevalence and characteristics of individuals susceptible to present with obstructive sleep apnea (OSA) is essential for developing targeted and efficient prevention and screening strategies. We included 27,210 participants aged ≥45 years old (50.3% women) from the Canadian Longitudinal Study on Aging. Using the STOP questionnaire combined to the percentage of body fat (%BF), we estimated the prevalence of individuals at high-risk for OSA in a sex and age-specific manner, and tested the relation with comorbidities, menopause and systemic inflammation. The prevalence was 17.5%, and was lower in women (13.1%) than in men (21.9%). A high level of high-sensitivity C-reactive protein was the strongest factor associated with OSA risk and this association was 1.3-2.3 times higher in women than in men. OSA risk increased with age, cardiovascular diseases, diabetes mellitus, anxio-depressive symptoms, asthma and arthritis. In women, post-menopausal status was associated with a high OSA risk. Nearly 1 adult out of 5 older than 45 is at risk for OSA in Canada. Comorbidities, menopause and systemic inflammation, more than age, explain increased OSA prevalence. Considering this high prevalence and associations with medical and mental comorbidities, health care practitioners should incorporate systematic OSA screening in their clinical procedures.

Indexed as

Sleep Apnea, ObstructiveAgedAgingCanadaFemaleHumansInflammationLongitudinal StudiesMaleMiddle AgedPrevalenceRisk Factors

Identifiers

PMID35332170
PMCPMC8948183

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.