Evidence map›Paper›PMID 35332092›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Factors for Differential Outcome Across Cancers in Clinical Molecule-Targeted Fluorescence Imaging.

Quan Zhou, Nynke S van den Berg, Wenying Kang, Jacqueline Pei, Naoki Nishio, Stan van Keulen, Myrthe A Engelen, Yu-Jin Lee, Marisa Hom, Johana C M Vega Leonel and 14 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Interim Phase II Results Using Panitumumab-IRDye800CW during Transoral Robotic Surgery in Patients with Oropharyngeal Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Trial
  3. Review
  4. Article
  5. Review
  6. The Use of Fluorescent Markers to Detect and Delineate Head and Neck Cancer: A Scoping Review.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 5 institutions in 3 countries.

Quan ZhouDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, California; qzh@stanford.edu e.rosenthal@vumc.org.
Nynke S van den BergDepartment of Otolaryngology, Stanford University School of Medicine, Stanford, California.
Wenying KangDepartment of Otolaryngology, Stanford University School of Medicine, Stanford, California.
Jacqueline PeiDepartment of Otolaryngology, Stanford University School of Medicine, Stanford, California.
Naoki NishioDepartment of Otolaryngology, Stanford University School of Medicine, Stanford, California.
Stan van KeulenDepartment of Otolaryngology, Stanford University School of Medicine, Stanford, California.
Myrthe A EngelenDepartment of Otolaryngology, Stanford University School of Medicine, Stanford, California.
Yu-Jin LeeDepartment of Otolaryngology, Stanford University School of Medicine, Stanford, California.
Marisa HomDepartment of Otolaryngology, Stanford University School of Medicine, Stanford, California.
Johana C M Vega LeonelDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, California.
Zachary HartDepartment of Otolaryngology, Stanford University School of Medicine, Stanford, California.
Hannes VogelDepartment of Pathology, Stanford University, Stanford, California.
Romain CayrolDepartment of Pathology, Stanford University, Stanford, California.
Brock A MartinDepartment of Pathology, Stanford University, Stanford, California.
Mark RoesnerStanford Health Care, Stanford University Medical Center, Stanford, California.
Glenn ShieldsStanford Health Care, Stanford University Medical Center, Stanford, California.
Natalie LuiDepartment of Cardiothoracic Surgery, Stanford University Medical Center, Stanford, California; and.
Melanie Hayden GephartDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, California.
Roan C RaymundoDepartment of Otolaryngology, Stanford University School of Medicine, Stanford, California.
Grace YiDepartment of Otolaryngology, Stanford University School of Medicine, Stanford, California.
Monica GranucciCancer Clinical Trials Office, Stanford University School of Medicine, Stanford, California.
Gerald A GrantDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, California.
Gordon LiDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, California.
Eben L RosenthalDepartment of Otolaryngology, Stanford University School of Medicine, Stanford, California; qzh@stanford.edu e.rosenthal@vumc.org.
Stanford University · USStanford Health Care · USStanford Medicine · USDelft University of Technology · NLNagoya University · JP

Funding

Optical Imaging to Improve Surgery & Targeted Therapy in Brain TumorsR01CA239257 · NCI · STANFORD UNIVERSITY · PI LI, GORDON, ROSENTHAL, EBEN L. · 2019 to 2023
$2.9M
Prototype optical device for image guided surgery with panitumumab-IRDye800R01CA190306 · NCI · STANFORD UNIVERSITY · PI ROSENTHAL, EBEN L. · 2015 to 2019
$2.6M
Clinician-scientist training program in otolaryngologyT32DC015209 · NIDCD · STANFORD UNIVERSITY · PI CHENG, ALAN GI-LUN · 2016 to 2021
$807k
NCI NIH HHS R01 CA190306NCI NIH HHS R01 CA239257NIDCD NIH HHS T32 DC015209
6 · The paper itself

Abstract

Clinical imaging performance using a fluorescent antibody was compared across 3 cancers to elucidate physical and biologic factors contributing to differential translation of epidermal growth factor receptor (EGFR) expression to macroscopic fluorescence in tumors.

Indexed as

Head and Neck NeoplasmsCell Line, TumorErbB ReceptorsHumansMargins of ExcisionOptical ImagingPanitumumabSquamous Cell Carcinoma of Head and NeckErbB ReceptorsPanitumumabclinical fluorescence imagingepidermal growth factor receptormulticancer surgical imagingpanitumumab-IRDye800physical and biologic factors

Identifiers

PMID35332092
PMCPMC9635681
OpenAlexW4220831336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.