ArticleAJNR. American journal of neuroradiology2022
Pulsatility Index in the Basal Ganglia Arteries Increases with Age in Elderly with and without Cerebral Small Vessel Disease.
Article in AJNR. American journal of neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Mapping Neurodegenerative Changes in Clinically Uncertain Parkinsonian Syndrome Patients Using Fast MR Spin TomogrAphy in Time-Domain (MR-STAT) Relaxometry at 3T.Journal of magnetic resonance imaging : JMRI · 2026Article
- Simultaneous Assessment of Intracranial Artery and Paravascular CSF Pulsation Using 3D Whole-Brain Diffusion-Prepared Cine bSSFP (DECAF) MRI.Magnetic resonance in medicine · 2026Article
- Pulsatility Assessment of Cerebral Perforating Arteries Using Submillimeter-Resolution Dual-VENC Phase-Contrast MRI at 3T.Journal of magnetic resonance imaging : JMRI · 2026Article
- A novel early imaging biomarker for glymphatic function: Cerebral cortical arterial pulsatility index from 2-Minute phase-contrast MRI.The journal of prevention of Alzheimer's disease · 2025Article
- The pulsing brain: state of the art and an interdisciplinary perspective.Interface focus · 2025Review
- Blood Flow Velocity Analysis in Cerebral Perforating Arteries on 7T 2D Phase Contrast MRI with an Open-Source Software Tool (SELMA).Neuroinformatics · 2025Article
- Efficient Fourier base fitting on masked or incomplete structured data.Frontiers in neuroimaging · 2025Article
- Vasomotion loss precedes impaired cerebrovascular reactivity and microbleeds in cerebral amyloid angiopathy.Brain communications · 2025Article
- Enlarged perivascular spaces in the basal ganglia are associated with arteries not veins.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Assessment of arterial pulsatility of cerebral perforating arteries using 7T high-resolution dual-VENC phase-contrast MRI.Magnetic resonance in medicine · 2024Article
- Assessment of Small Vessel Function Using 7T MRI in Patients With Sporadic Cerebral Small Vessel Disease: The ZOOM@SVDs Study.Neurology · 2024Observational
- Regional differences in the link between water exchange rate across the blood-brain barrier and cognitive performance in normal aging.GeroScience · 2024Article
- In vivo detection of penetrating arteriole alterations in cerebral white matter in patients with diabetes with 7 T MRI.Magnetic resonance imaging · 2023Article
- Advances in differential diagnosis of cerebrovascular diseases in magnetic resonance imaging: a narrative review.Quantitative imaging in medicine and surgery · 2023Review
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Authors and funding
10 authors at 4 institutions in 5 countries.
Funding
Abstract
background and purposeCerebral small vessel disease contributes to stroke and cognitive impairment and interacts with Alzheimer disease pathology. Because of the small dimensions of the affected vessels, in vivo characterization of blood flow properties is challenging but important to unravel the underlying mechanisms of the disease. MATERIALS AND
methodsA 2D phase-contrast sequence at 7T MR imaging was used to assess blood flow velocity and the pulsatility index of the perforating basal ganglia arteries. We included patients with cerebral amyloid angiopathy (
resultsOlder age was related to a greater pulsatility index, irrespective of cerebral small vessel disease. In hypertensive arteriopathy, there was an association between lower blood flow velocity of the basal ganglia and the presence of peri-basal ganglia WM hyperintensities.
conclusionsOur results suggest that age might be the driving factor for altered cerebral small vessel hemodynamics. Furthermore, this study puts cerebral small vessel disease downstream pathologies in the basal ganglia region in relation to blood flow characteristics of the basal ganglia microvasculature.
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