Evidence map›Paper›PMID 35331272›Full record

ArticleReproductive health2022

Birth rate after major trauma in fertile-aged women: a nationwide population-based cohort study in Finland.

Matias Vaajala, Ilari Kuitunen, Lauri Nyrhi, Ville Ponkilainen, Maiju Kekki, Tuomas T Huttunen, Ville M Mattila

Open access · goldAbstract read
In one paragraph

Article in Reproductive health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Delivery mode and subsequent birth rate: A nationwide register-based analysis in Finland.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  2. Article
  3. Caesarean Section for Orthopedic Indications.Journal of clinical medicine · 2023
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Matias VaajalaFaculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland. Matias.vaajala@tuni.fi.ORCID http://orcid.org/0000-0002-1294-6173
Ilari KuitunenDepartment of Pediatrics, Mikkeli Central Hospital, Mikkeli, Finland.
Lauri NyrhiFaculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Ville PonkilainenDepartment of Surgery, Central Finland Central Hospital Nova, Jyvaskyla, Finland.
Maiju KekkiDepartment of Obstetrics and Gynecology, Tampere University Hospital Tampere, Tampere, Finland.
Tuomas T HuttunenFaculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Ville M MattilaFaculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Tampere University · FICentral Finland Health Care District · FIUniversity of Eastern Finland · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo date, only a few small studies have assessed the effects of major orthopedic traumas on the subsequent birth rate in fertile-aged woman. We assessed the incidences of traumatic brain injury (TBI) and fractures of the spine, pelvis, and hip or thigh and evaluated their association with the birth rate in fertile-aged woman.

methodsIn this retrospective register-based nationwide cohort study, data on all fertile-aged (15-44 years of age) women who sustained a TBI or fracture of the spine, pelvis, hip or thigh between 1998 and 2013 were retrieved from the Care Register for Health Care. A total of 22,780 women were included in TBI group, 3627 in spine fracture group, 1820 in pelvic fracture group, and 1769 in hip or thigh fracture group. The data were subsequently combined with data from the National Medical Birth Register. We used Cox regression model to analyze the hazard for a woman to give birth during 5-year follow-up starting from a major trauma. Women with wrist fractures (4957 women) formed a reference group. Results are reported as hazard ratios (HR) with 95% confidence intervals (CI).

resultsDuring 5-year follow-up after major trauma, 4324 (19.0%) women in the TBI group, 652 (18.0%) in the spine fracture group, 301 (16.5%) in the pelvic fracture group, 220 (12.4%) in the hip or thigh fracture group, and 925 (18.7%) in the wrist fracture group gave birth. The cumulative birth rate was lower in the hip or thigh fracture group in women aged 15-24 years (HR 0.72, CI 0.58-0.88) and 15-34 years (HR 0.65, CI 0.52-0.82). Women with pelvic fracture aged 25-34 years also had a lower cumulative birth rate (HR 0.79, CI 0.64-0.97). For spine fractures and TBIs, no reduction in cumulative birth rate was observed. Vaginal delivery was the primary mode of delivery in each trauma group. However, women with pelvic fractures had higher rate of cesarean section (23.9%), when compared to other trauma groups.

conclusionsOur results suggest that women with thigh, hip, or pelvic fractures had a lower birth rate in 5-year follow-up. Information gained from this study will be important in clinical decision making when women with previous major trauma are considering becoming pregnant and giving birth.

Indexed as

Birth RateCesarean SectionAdolescentAdultAgedCohort StudiesFemaleFinlandHumansPregnancyRetrospective StudiesYoung Adult

Identifiers

PMID35331272
PMCPMC8944167
OpenAlexW4220905376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.