ArticleMalaria journal2022
Modelling new insecticide-treated bed nets for malaria-vector control: how to strategically manage resistance?
Article in Malaria journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 25 citations in OpenAlex.
- Evolutionary and epidemiological considerations for anthelmintic treatments in ruminant livestock.International journal for parasitology. Drugs and drug resistance · 2026Article
- Impact of insecticide resistance evolution on malaria vector control.PLoS computational biology · 2026Article
- Optimizing insecticide deployment strategies to delay quantitative resistance in mosquito populations.Journal of mathematical biology · 2026Article
- A proof-of-concept experimental-theoretical model to predict pesticide resistance evolution.Heredity · 2025Article
- Simulating dynamic insecticide selection pressures for resistance management in mosquitoes assuming polygenic resistance.PLoS computational biology · 2025Article
- The impact of insecticide decay on the rate of insecticide resistance evolution for monotherapies and mixtures.Malaria journal · 2025Article
- Laboratory evaluation of the contact irritancy of a clothianidin solo formulation vs. clothianidin-deltamethrin mixture formulations for indoor residual spraying against pyrethroid-resistant Anopheles gambiae sensu lato.Parasites & vectors · 2024Article
- Biological lessons for strategic resistance management.Evolutionary applications · 2023Article
- Insecticide resistance management strategies for public health control of mosquitoes exhibiting polygenic resistance: A comparison of sequences, rotations, and mixtures.Evolutionary applications · 2023Article
- Beyond redundant kill: A fundamental explanation of how insecticide mixtures work for resistance management.Pest management science · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe program to eradicate malaria is at a critical juncture as a new wave of insecticides for mosquito control enter their final stages of development. Previous insecticides have been deployed one-at-a-time until their utility was compromised, without the strategic management of resistance. Recent investment has led to the near-synchronous development of new insecticides, and with it the current opportunity to build resistance management into mosquito-control methods to maximize the chance of eradicating malaria.
methodsHere, building on the parameter framework of an existing mathematical model, resistance-management strategies using multiple insecticides are compared to suggest how to deploy combinations of available and new insecticides on bed nets to achieve maximum impact.
resultsAlthough results support the use of different strategies in different settings, deploying new insecticides ideally together in (or at least as a part of) a mixture is shown to be a robust strategy across most settings.
conclusionsSubstantially building on previous works, alternative solutions for the resistance management of new insecticides to be used in bed nets for malaria vector control are found. The results support a mixture product concept as the most robust way to deploy new insecticides, even if they are mixed with a pyrethroid that has lower effectiveness due to pre-existing resistance. This can help deciding on deployment strategies and policies around the sustainable use of these new anti-malaria tools.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.