Evidence map›Paper›PMID 35331095›Full record

ArticleCurrent cardiology reviews2022

Obesity Paradox in Atrial Fibrillation and its Relation with the New Oral Anticoagulants.

André Inocêncio Novaes Lima Filho, Mariana Costa do Rego Barros, Alice Almeida de Barros Guimarães, Dário Celestino Sobral Filho

Open access · greenAbstract read
In one paragraph

Article in Current cardiology reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

André Inocêncio Novaes Lima FilhoFaculty of Medical Sciences, Universidade de Pernambuco, Recife, Brazil.
Mariana Costa do Rego BarrosFaculty of Medical Sciences, Universidade de Pernambuco, Recife, Brazil.
Alice Almeida de Barros GuimarãesFaculty of Medical Sciences, Universidade de Pernambuco, Recife, Brazil.
Dário Celestino Sobral FilhoFaculty of Medical Sciences, Universidade de Pernambuco, Recife, Brazil.
Universidade de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity, a chronic disease established as a global epidemic by the World Health Organization, is considered a risk factor for atrial fibrillation (AF), the most common sustained cardiac arrhythmia, which has high morbidity and mortality. Although both obesity and AF are diseases associated with negative outcomes, studies have shown the presence of an obesity paradox, in which patients with a high body mass index (BMI) and AF have a better prognosis than patients with a normal BMI. Despite the fact that the mechanisms that lead to this paradox are still uncertain, adequate anticoagulation in obese patients seems to play an important role in reducing adverse events in this group. In this perspective article, the authors discuss the relationship between new oral anticoagulants (NOACs), namely, apixaban, edoxaban and rivaroxaban (factor Xa inhibitors) and dabigatran (direct inhibitor of thrombin), and the obesity paradox, seeking to deepen the understanding of the mechanism that leads to this paradox.

Indexed as

Atrial FibrillationStrokeAdministration, OralAnticoagulantsDabigatranFactor Xa InhibitorsHumansObesityPyridonesRivaroxabanThrombinAnticoagulantsDabigatranFactor Xa InhibitorsPyridonesRivaroxabanThrombinapixabanatrial fibrillationdabigatranedoxabannew oral anticoagulantsObesityobesity paradoxrivaroxaban

Identifiers

PMID35331095
PMCPMC9896420
OpenAlexW4220683983

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.